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    UniteToFight2024 Long Covid and ME/CFS conference, 15th and 16th May 2024

    Maybe when the transcript becomes available it'll shed some light.
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    A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection, 2024, Singh et al.

    Can't believe they let the mice read that article by George Monbiot.
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    UniteToFight2024 Long Covid and ME/CFS conference, 15th and 16th May 2024

    From the first page of selected quotes: "It appears that about 50% patients have both MS and ME/CFS" - Prof. Dr. Ron Davis ??
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    Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue, 2024, Hosp et al

    "the time span between positive SARS-CoV-2 PCR and the cerebral MRI did not explain alterations of gray matter DMI parameters or spatial distribution of V-extra changes between the PCC and UPC groups. Thus, one could speculate on a slow or even non-reversibility of microstructural changes...
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    Changes in interoceptive accuracy related to emotional interference in somatic symptom disorder, 2024, Lee et al

    Small sample, "no significant difference in the absolute values of IA between patients with SSD and healthy controls, regardless of the condition". It's just statistical noise. If they'd done it on another day they might have got results that went the opposite way (more interference with...
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    United Kingdom: News from BACME - British Association of Clinicians in ME/CFS

    In contrast, from the DecodeME transcript above: :emoji_clap:
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    Muscle abnormalities worsen after post-exertional malaise in long COVID, 2023/4, Wüst, van Vugt, Appelman et al

    "#Longcovid related #PEM question: do female patients experience PEM symptoms that align with the menstrual cycle?" In my case, in 2.5 years of long Covid: no.
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    Trial Report Examining well-being and cognitive function in people with long Covid and ME/CFS, and age-matched healthy controls, 2024, Sanal-Hayes

    The Cognitron/GBIT study found measurable, significant post-Covid cognitive impairment with more than 100,000 participants (and that didn't even include a more severe cohort). These researchers trying to say they've disproved that on the basis of 50 people doing a Stroop test is just sad.
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    Trial Report Examining well-being and cognitive function in people with long Covid and ME/CFS, and age-matched healthy controls, 2024, Sanal-Hayes

    "Long COVID and ME/CFS cause impaired well-being and cognitive function", but "People with Long COVID and ME/CFS have... comparable cognitive function when compared to controls" and "Our cognitive function findings do not support the existing literature that suggest cognitive impairment...
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    Resources on why the Name “CFS” is problematic and “ME” or “ME/CFS” is recommended.

    It's not actually citing any of the sources directly, it's just generating text that looks as if it does, because those sources are somewhere in the training data that gives it its probabilities for each word following the previous one. That's why it lists five "citations" but only 1, 3 and 4...
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    Protocol Trial registration: Low-dose Naltrexone for Post-COVID Fatigue Syndrome, 2022, Luis Nacul, British Columbia Women's Hospital & Health Centre

    That was my thought too. Especially as it takes several weeks just to work up to the full dose.
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    People with Inflammatory Bowel Disease Prefer Cognitive Behavioral Therapy for Fatigue Management: A Conjoint Analysis 2024 Emerson et al

    Another nugget from the paper: As Inigo Montoya might say: You keep using that word, "promising". I do not think it means what you think it means.
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    People with Inflammatory Bowel Disease Prefer Cognitive Behavioral Therapy for Fatigue Management: A Conjoint Analysis 2024 Emerson et al

    The participants were asked to say which one they preferred out of pairs of short descriptions of unnamed therapies, e.g. 'A psychological therapy focused on finding solutions rather than focusing on the problem' or 'A psychological therapy focused on the links between our thought and how we...
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    USA: The RECOVER Initiative - Long Covid research

    Slide 19 of the presentation posted here: https://www.s4me.info/threads/usa-the-recover-initiative-long-covid-research.30525/page-7#post-531223 suggests it's a fairly energy-intensive process in itself - "Task analysis to identify and prioritize illness-impacted tasks and functions" and...
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    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    re 'lack of accountability' I was thinking of how it resembles situations I've encountered in the area of special needs education and children's services, where systems created for helpful purposes become mechanisms for keeping people at arm's length from the decision-makers and preserving the...
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    Sense about Science: Join our talks on science, scepticism and free speech (Garner et al)

    Nice of him to set out how he's adopted various positions on the 'facts' according to what he's experienced emotionally at various times. I wouldn't bet against him doing another 180 at some point.
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    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    it comes down to lack of accountability.
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    Experience with LDN? low dose naltrexone

    yep - I've had a small improvement in cognitive function since taking LDN but that could easily be coincidence. I'm coming up to a year on it, so will stop for a bit at that point and see if I feel any different. It definitely affected my sleep in the first few weeks of building up the dose...
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    The People's Pharmacy: Mending Mistrust–Can We Rebuild Faith in Medicine?

    I don't think that's ever really been true (like most claims about how life was better/simpler in the past!). There are endless stories going back centuries about dodgy doctors and snake oil pushers.
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