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Now vastly more complicated and voluminous due to AI, and only likely to quickly get even worse.

who do not conduct any quality controls on submissions Maybe they are just following the example of the established mainstream journals (at least in some areas)?

Exactly. This is one of those studies that will tell us something useful, maybe even important, regardless of the actual results. Strong, weak, null. They are all meaningful outcomes that will help focus future research efforts. All that matters is that it is methodologically robust. Thanks...

Interesting. :nerd:

I don't think this necessarily holds.

Functional neurological disorder (FND) presents with neurological symptoms lacking a structural correlate and is thought to result from brain network dysfunction. Despite advances in understanding its pathophysiology, several knowledge gaps exist. The main one being the mystery of how the FND...

Mental health–related visits and visits for ill-defined symptoms and signs were elevated 14 to 15 years before MS onset, followed by neurology and ophthalmology consultations (8-9 years before onset) and musculoskeletal, sensory, and nervous system visits (4-8 years before onset). Which could...

There are few things I want more in this world than a robust in vitro model for PEM. That really would be a game changer for research and for us.

There must be accountability. Letting those responsible for this grotesque catastrophe just slink away quietly into a comfortable retirement is totally unacceptable. All that will do is let it happen again to another group of innocent victims. See FND.

The whole FND project really does just get more and more dystopian and cruel, doesn't it. Their lost for power, at whatever cost, is insatiable.

Interesting. Hope they can replicate it in a much larger sample.

That would be the late Mansel Aylward.

Thank you, @Hilda Bastian, for not letting this go. Every time I start thinking the 'authorities' couldn't get any worse, there they go and prove me wrong. Again. :mad:

It is how they avoid taking any responsibility for delivering something actually useful for the patient. 'Just asking questions.'

'This study provides early evidence that psychological, nutritional and combined techniques for the treatment of ME/CFS may influence symptomatology, fatigue, function and perceived control. However, these results must be viewed with caution as the allocation to groups was not randomised, there...

Maybe it is because I grew up in an analog world, long before any of this modern self-surveillance tech was available, but I just can't get into all this stuff. I just can't see the value in it. Maybe heart rate monitoring has some limited value. Maybe. But if we don't have any clear biomarkers...

With friends like these... :mad:

Background: Multiple Chemical Sensitivity (MCS) is a complex, disabling condition marked by non-specific symptoms in response to low-level chemical exposures. It often leads to substantial impairments in quality of life, psychological health, and daily functioning. Although non-pharmacological...

Causal complexity No, it's causal opacity that is the problem. The lack of demonstrated causal pathways. It is ignorance, not complexity, that characterises the diagnosis of persistent physical symptoms, including whether the diagnosis itself has any epistemological validity and clinical value.

The medical profession, from day one of med school through to at least a decade or so post-graduation, selects ruthlessly for stamina. Those who can't hack it get weeded out early, at least from the clinical stream. Those left on their feet tend to have less direct experience and understanding...