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Vaccination induces HIV broadly neutralizing antibody precursors in humans https://www.science.org/doi/10.1126/science.add6502

Before reading this paper, I had no idea that blood vessels had blood vessels. The human body is amazing.

Darn it, I wish there was at least ONE aspect of ME pathology that had rock solid research, meaning replicated multiple times. I'm tired of the lack of research into a condition that's so profoundly disabling.

This is a major problem with the concept of FND. It seems to be a true clinical entity. But doctors misdiagnose a huge number of people with it, either by formally saying, "You have FND," or more commonly and indirectly, insinuations it's just anxiety.

Long Covid is distorting the labor market — and that’s bad for the U.S. economy https://www.cnbc.com/2022/12/08/long-covid-is-distorting-the-labor-market-hurting-the-us-economy.html Estimates of how many people are unable to work due to long Covid vary widely. One person they cited calculated...

The authors don't seem to have a modern understanding of FND. We don't call it conversion disorder anymore. If I understand the modern research, it points to an issue in the brain, perhaps with connectivity, so it's unsurprising that moods/stress can be involved. (Mental states affect my tics...

This is a hypothesis paper, meaning it's a new perspective on existing research. The idea that OI is caused by a specific sort of vascular dysfunction is pretty novel and interesting. What types of experiment could help confirm or disprove it?

Using control with a less harmful virus is a good design.

I made some small contributions to what later became the AV1 video codec, widely used to compress video by companies such as YouTube and Netflix. I worked on MSA LUNAR, a device that can help locate firefighters in danger. When I was 17 I built high-performance FM and TV antennas from designs I...

I read this garbage so you don't have to. She discusses both the psychosomatic and physical models of ME and LC with a strong bias towards them both being psychosomatic, but in a more modern sense where emotions are claimed to make something actually go wrong, like FND. They feature a story of a...

I used to think of doctors as especially competent because of their rigorous training and role in protecting people's lives. I've seen many other professionals mess things up. Software developers building entire systems out of cheap hacks, electricians doing work that isn't up to code, useless...

This is absolutely not how I modeled my own energy levels when I was a healthy autistic person. The main factors I considered were demands on social interaction, executive function, and sensory processing.

This is pretty bad. You can't analyze research in a dozen different diseases and apply it to long Covid by just compiling it.

The WHO guideline actually shows a good understanding of PEM. They devote an entire page to it and explicitly recommend against GET (pg. 110):

I've seen this AI do remarkable things. Someone asked it to write a simple program in Rust and it did, the only error being omitting a statement to include a library.

It sounds like they're just hosting a bunch of meetings between ME, long Covid, etc. advocacy groups. I see a possibility for benefits, but not concrete or direct ones.

That's the problem with medical marijuana. There's no real evidence base for it. And it's hard to research because of legal issues.

I've observed a trend towards increasing use of ME, and it's continuing: They want to set up Centers of Excellence for long Covid: Due to the lack of treatments, the main benefit will be not harming patients with CBT/GET. I hope this gets expanded to ME/CFS, as getting specialist care is...

I'm disappointed nobody has put this into action. I would absolutely want samples of my tissue used for ME research if I die when ME is still poorly understood.

Unfortunately, no mention of PEM. They also seem to downplay the effect of long Covid on previously healthy people: In context, they balance this with anecdotes of sidelined athletes and a call for more research, but I still think this sentence is unjustified. Also, no mention of PEM. Most of...