cell type enrichtment

  1. ME/CFS Science Blog

    Dropviz: the mouse brain atlas, Saunders et al. 2018.

    I had a go at matching genetic data on ME/CFS with the gene expression data from Dropviz. This is the paper that discovered the eccentric medium spiny neuron (discussed here). It's a mouse brain atlas with RNA data from 0.69 million cells. The main publication is Saunders et al. 2018. but...
  2. ME/CFS Science Blog

    Genetic identification of brain cell types underlying schizophrenia, Skene, 2018

    Abstract With few exceptions, the marked advances in knowledge about the genetic basis of schizophrenia have not converged on findings that can be confidently used for precise experimental modeling. By applying knowledge of the cellular taxonomy of the brain from single-cell RNA sequencing, we...
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