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Glutamate transporters have a chloride channel with two hydrophobic gates (2021) Chen et al

Discussion in 'Other health news and research' started by Colin, Feb 19, 2021.

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  1. Colin

    Colin Established Member (Voting Rights)

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    Location:
    Brisbane, Australia
    Abstract:
    Paywall: Nature

    Popular Article (with cool animation): A 'twisted elevator' could be key to understanding neurological diseases
     
    Last edited: Feb 19, 2021
    alktipping, Trish, Perrier and 4 others like this.
  2. Mithriel

    Mithriel Senior Member (Voting Rights)

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    Research like this leaves me not knowing whether to laugh or cry. There is so much still to learn about cellular function, how it works and what can go wrong with it, yet medicine screams about FND and MUS with their patronising dismissal of patients.
     
    alktipping, Trish, Colin and 2 others like this.
  3. Joan Crawford

    Joan Crawford Senior Member (Voting Rights)

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    546
    Location:
    Warton, Carnforth, Lancs, UK
    Thanks for posting this abstract.

    Glutamate control / regulation is perhaps off in pwME and I hope this type of research excites ME researchers to explore and so forth, if they aren't already.

    I have a paper by one of the co-authors of this paper (Ryan from 2013) detailing the mechanisms of glutamate transport. It's too big to attach. Here is the link: https://journals.physiology.org/doi/pdf/10.1152/physrev.00007.2013
     
    Amw66, Mithriel, alktipping and 2 others like this.
  4. Kitty

    Kitty Senior Member (Voting Rights)

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    UK
    Fascinating! Thanks for posting it, @Colin.
     
    alktipping likes this.

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