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Search Results for Query: HLA-DQA1

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  1. forestglip
    Post

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    100% of ME/CFS and 73.3% of LC had PEM. I think the genes/pathways most likely to be important would be the ones significant in both LC and...
    Post by: forestglip, Oct 23, 2024 in forum: ME/CFS research
  2. SNT Gatchaman
    Post

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    ...counts) from supp file 1 and reordering/transposing — For HLA-DQA1 HC01 10.6659423 HC02 9.7885739 HC03 11.2015097 HC04 10.3171179 HC05...
    Post by: SNT Gatchaman, Oct 23, 2024 in forum: ME/CFS research
  3. forestglip
    Post

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    I'm a bit confused about whether the HLA genes are differentially expressed in ME/CFS. That statement seems to say so, but Figures 2 and 3 don't...
    Post by: forestglip, Oct 22, 2024 in forum: ME/CFS research
  4. SNT Gatchaman
    Post

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    HLA-DQA1 and HLA-DQB1 have been highlighted previously, eg — Immunometabolic changes and potential biomarkers in CFS peripheral immune cells...
    Post by: SNT Gatchaman, Oct 22, 2024 in forum: ME/CFS research
  5. SNT Gatchaman
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    See also Immune exhaustion in ME/CFS and long COVID (2024, JCI Insight)
    Post by: SNT Gatchaman, Oct 22, 2024 in forum: Long Covid research
  6. SNT Gatchaman
    Post

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    Post by: SNT Gatchaman, Oct 22, 2024 in forum: ME/CFS research
  7. SNT Gatchaman
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    In Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing (2024, Journal of...
    Post by: SNT Gatchaman, Oct 14, 2024 in forum: Long Covid research
  8. SNT Gatchaman
    Post

    Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing, 2024, Sun et al

    Results cont'd, with added GeneCards links — Upregulated genes enriched in phagocytosis related function in monocytes Cell-cell...
    Post by: SNT Gatchaman, Oct 14, 2024 in forum: ME/CFS research
  9. S4ME News
    Post

    News in Brief - October 2024

    ...of Long COVID identified three genome-wide significant loci (HLA-DQA1 and HLA-DQB, ABO, BPTF:KPAN2:C17orf58). Functional analysis of these...
    Post by: S4ME News, Oct 13, 2024 in forum: Weekly ME news in brief
  10. Nightsong
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    ...broad self-defined LC definition. It may be worthy of note that HLA-DQA1 was once potentially implicated in CFS; there was a small (n=49)...
    Post by: Nightsong, Oct 12, 2024 in forum: Long Covid research
  11. hotblack
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    Yes it’s an audio summary, sorry if that wasn’t clear. I can easily post the text too if people prefer? (quoted below) So I don’t completely...
    Post by: hotblack, Oct 12, 2024 in forum: Long Covid research
  12. Nightsong
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    Post by: Nightsong, Oct 10, 2024 in forum: Long Covid research
  13. Nightsong
    Post

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    ...GWAS of Long COVID identified three genome-wide significant loci (HLA-DQA1 and HLA-DQB, ABO, BPTF:KPAN2:C17orf58). Functional analysis of these...
    Post by: Nightsong, Oct 10, 2024 in forum: Long Covid research
  14. Paraprosdokian
    Post

    Hypothesis Hypocortisolemic ASIA: A vaccine-and chronic infection-induced syndrome behind the origin of long COVID and ME, 2024, Ruiz-Pablos et al

    @Manuel, thank you for this paper. I think it draws together many threads. I had a question about the HLA genes though. You point out that HLA...
    Post by: Paraprosdokian, Jul 17, 2024 in forum: ME/CFS research
  15. Andy
    Post

    Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review 2022 Tziastoudi et al

    ...were significantly affected. We found that ACE, HLA-A, HLA-C, HLA-DQA1, HLA-DRB1, and TYK2 are the common genes that gave significant results....
    Post by: Andy, Oct 7, 2022 in forum: ME/CFS research
  16. Hoopoe
    Post

    A look at my whole genome sequencing results

    Some genes have a large number of variants. For example my HLA-DQA1 gene has 1244 :eek:. Here the software highlights 17 of them as being of...
    Post by: Hoopoe, Aug 19, 2022 in forum: Laboratory and genetic testing, medical imaging
  17. Hutan
    Post

    CD4+ Cytotoxic T Cells Involved in the Development of EBV-Associated Diseases, 2022, Ruiz-Pablos

    (I should have said, thanks for coming here @Manuel.) I'm not discounting the main idea, even if the proposed risk haplotypes for ME/CFS don't pan...
    Post by: Hutan, Jul 27, 2022 in forum: ME/CFS research
  18. Hoopoe
    Post

    A look at my whole genome sequencing results

    ...increased risk for multiple sclerosis. PS: also many variants in HLA-DQA1. I also have one of the IDO2 variants reported by Phair as...
    Post by: Hoopoe, Jul 22, 2022 in forum: Laboratory and genetic testing, medical imaging
  19. Andy
    Post

    Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis, 2019, Engdahl et al

    Open access, https://www.frontiersin.org/articles/10.3389/fimmu.2019.02715/full Press release,...
    Post by: Andy, Nov 26, 2019 in forum: Other health news and research
  20. alicec
    Post

    HLA Frequencies

    I had to refresh my memory about what the 3 sets of numbers mean - ie as used by Shoemaker. You can see more about that here and here. So the...
    Post by: alicec, Jun 24, 2018 in forum: Other treatments
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