I think Flottorp and others at FHI at one point (I think as part of the whole issue with getting the Lightning Process trial through the ethics...
What’s the story on that Canada LC guideline? Was it past reviews that got them that seat at the table or the absence of Nice there and the...
Noted.
...the use of exercise therapy in CFS (one of the others being the PACE trial). The Cochrane review is often cited by people wanting to encourage...
All of that still being salvageable, while yet another "scrap-it and upgrade" became ruinous and also pandemically unaffordable, plus all those...
One caveat is that PACE is not really the trial that is driving the effect in the meta-analysis (it often found lower effects than the...
Moderator note: Since Cochrane cancelled the update of the Larun 2019 review and republished it unchanged as the 2024 review there has been much...
I think it plays a role but not that big. Even if PACE were retracted, there's been loads of new trials held since. All small and with even lower...
...read Crawley eg al 2013 which was basically another arm of the pace trial except they found no result for physical function even then just the...
It's also not really convincing in itself, as the PACE trial is definitely taught at more universities as a great example of high quality...
' Just to be clear on this, I only know of this at my own place, the School of Public Health at UC Berkeley. It has been used in epidemiology...
...illnesses, there's a big economic incentive. The history of the PACE trial suggests that chiming with strong political priorities doesn't do...
...for ME. They were for chronic fatigue and so legitimate. The PACE trial was a nice demonstration that CBT and GET do not work, whether you...
Are you condoning the use of the Oxford criteria for ME? Why conflate Fibromyalgia with ME? They are opposites, Fibromyalgia is a...
...able to see more than 1% of patients anyway. Which is what the PACE trial showed, and not just for ME/CFS but for generic chronic fatigue. This...
...why after so many years that more is not done about this. The PACE trial authors took apps away for good reason and that also includes Crawley...
...priority. This slightly feels like an informal re-run of the pace trial if done wrong. But more to the point why is this the biggest priority?...
Raijmaker is the researcher who suggested that CBT was helpful for Q-fever fatigue syndrome (and that it has been proven to be helpful for CFS)...
...up the meta-analysis. The only 2 randomized studies are the PACE trial and this small Belgian study: https://pubmed.ncbi.nlm.nih.gov/26356665/...
...elaborate on psychological intervention studies after the PACE trial that found benefit for some patients? Could it not be of use for some...
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