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Search Results for Query: HLA-DQB1

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  1. Dolphin
    Thread

    Immune cell proteomes of Long COVID patients have functional changes similar to those in ME/Chronic Fatigue Syndrome, 2023, Peppercorn, Tate et al.

    https://www.researchsquare.com/article/rs-3335919/v1 Article Immune cell proteomes of Long COVID patients have functional changes similar to...
    Thread by: Dolphin, Sep 30, 2023, 11 replies, in forum: ME/CFS research
  2. Andy
    Thread

    Review DNA methylation signatures of functional somatic syndromes: Systematic review, 2023, Fischer et al

    ...site located to LY86 and hypermethylated sites within HLA-DQB1 were found. In genome-wide studies in fibromyalgia syndrome, differential...
    Thread by: Andy, Aug 3, 2023, 5 replies, in forum: ME/CFS research
  3. SunnyK
    Post

    Aripiprazole - Abilify

    Jaybee, I am curious about your ME diagnosis. It seems very specific (to a non-scientist), and I'm wondering if you can explain the designation...
    Post by: SunnyK, Feb 1, 2023 in forum: Drug and supplement treatments
  4. Andy
    Post

    Thesis Thesis: Investigating the Genetic and Immunological Aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022 Dibble

    This thesis describes two investigations into the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), specifically its genetic...
    Post by: Andy, Jan 30, 2023 in forum: ME/CFS research
  5. Kalliope
    Post

    Norway: Articles from TV2 about ME. Interviews with researchers as Fluge, Rekeland, Sommerfelt, Kielland and an interesting patient case

    ...tagged by the alleles HLA-C*07:04 (OR 2.1 [95% CI 1.4–3.1]) and HLA-DQB1*03:03 (OR 1.5 [95% CI 1.1–2.0]). These alleles were carried by 7.7%...
    Post by: Kalliope, Oct 25, 2022 in forum: General ME/CFS news
  6. Jaybee00
    Post

    CD4+ Cytotoxic T Cells Involved in the Development of EBV-Associated Diseases, 2022, Ruiz-Pablos

    Yes. “Patients positive for HLA-DQB1*03:03 and/or HLA-C*07:04 (n = 12) had significantly higher response rate compared to patients negative for...
    Post by: Jaybee00, Jul 27, 2022 in forum: ME/CFS research
  7. Hutan
    Post

    CD4+ Cytotoxic T Cells Involved in the Development of EBV-Associated Diseases, 2022, Ruiz-Pablos

    (I should have said, thanks for coming here @Manuel.) I'm not discounting the main idea, even if the proposed risk haplotypes for ME/CFS don't pan...
    Post by: Hutan, Jul 27, 2022 in forum: ME/CFS research
  8. Hutan
    Post

    CD4+ Cytotoxic T Cells Involved in the Development of EBV-Associated Diseases, 2022, Ruiz-Pablos

    I had the impression that HLA alleles had been looked at in ME/CFS, and nothing had showed up with the frequency we would expect if these alleles...
    Post by: Hutan, Jul 27, 2022 in forum: ME/CFS research
  9. Hoopoe
    Post

    A look at my whole genome sequencing results

    ...the interesting findings so far is a series of mutations in the HLA-DQB1 gene, and one in the HLA-DRB1 gene which are all associated with...
    Post by: Hoopoe, Jul 22, 2022 in forum: Laboratory and genetic testing, medical imaging
  10. Andy
    Post

    No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for (ME/CFS), 2022, Ueland et al

    ...important human leucocyte antigen (HLA) genes HLA-C and HLA-DQB1 in ME/CFS. Furthermore, a genome-wide genetic association study in 42 ME/CFS...
    Post by: Andy, Jul 13, 2022 in forum: ME/CFS research
  11. LarsSG
    Post

    Immunogenetic Studies In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2022, Hajdarevic PhD thesis

    ...that reported associations between ME/CFS and HLA-C: 07: 04 and HLA-DQB1: 03: 03 alleles. The HLA (human leukocyte antigen) region consists a...
    Post by: LarsSG, Jun 19, 2022 in forum: ME/CFS research
  12. Trish
    Post

    News in Brief - November 2021

    Week beginning 15th November 2021 Post 1 of 2 posts News, articles and advocacy Massachusetts ME/CFS & FM Association "Advances in our...
    Post by: Trish, Nov 21, 2021 in forum: Weekly ME news in brief
  13. Trish
    Post

    Epstein-Barr Virus and the Origin of Myalgic Encephalomyelitis or Chronic Fatigue Syndrome, 2021, Manuel Ruiz-Pablos et al.

    Thanks for posting this, @Manuel. Here's the first section of the paper, which I have split into shorter paragraphs for ease of reading:...
    Post by: Trish, Nov 15, 2021 in forum: ME/CFS research
  14. Kalliope
    Post

    Fine mapping of the major histocompatibility complex (MHC) in (ME/CFS) suggests involvement of both HLA class I and class II loci, 2021, Hajdarevic

    ...HLA class I and II associations. • Positive association of HLA-DQB1 amino acid residue 57D. In conclusion, we report, to the best of our...
    Post by: Kalliope, Aug 18, 2021 in forum: ME/CFS research
  15. Amw66
    Post

    Fine mapping of the major histocompatibility complex (MHC) in (ME/CFS) suggests involvement of both HLA class I and class II loci, 2021, Hajdarevic

    @Simon M can you provide a plain english version - no problem if it takes a while.
    Post by: Amw66, Aug 18, 2021 in forum: ME/CFS research
  16. Andy
    Thread

    Fine mapping of the major histocompatibility complex (MHC) in (ME/CFS) suggests involvement of both HLA class I and class II loci, 2021, Hajdarevic

    ...was located within the HLA-DQ gene region, most likely due to HLA-DQB1, particularly the amino acid position 57 (aspartic acid/alanine) in the...
    Thread by: Andy, Aug 18, 2021, 15 replies, in forum: ME/CFS research
  17. Dolphin
    Post

    Human leukocyte antigen associations in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and immune modulating treatment, 2021, Lande

    ...a significantly higher prevalence of the alleles HLA-C*07:04 and HLA-DQB1*03:03 among 426 patients than among 4511 healthy controls. 22 out of...
    Post by: Dolphin, May 24, 2021 in forum: ME/CFS research
  18. Jaybee00
    Post

    Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Fluge, Mella et al 2020

    Yeah just saw that. Dr. Mignot identified genetic factors predisposing to human narcolepsy, such as human leukocyte antigenHLA DQB1*06:02 and...
    Post by: Jaybee00, May 11, 2021 in forum: ME/CFS research
  19. Kalliope
    Post

    Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Fluge, Mella et al 2020

    ...a significantly higher prevalence of the alleles HLA-C*07:04 and HLA-DQB1*03:03 among 426 patients than among 4511 healthy controls. 22 out of...
    Post by: Kalliope, May 11, 2021 in forum: ME/CFS research
  20. Hutan
    Post

    The possibility of autoimmunity or auto-reactivity in ME/CFS

    ...HLA-DRB1 and HLA-DQB1 appear to be associated with Graves disease susceptibility. I was idly googling for any information about Campath...
    Post by: Hutan, Jan 13, 2021 in forum: Possible causes and predisposing factor discussion
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