Hi, No not planning to come of it now, but agree with your point about potential withdrawal issues. HLA risk alleles for ME/CFS discussed in...
I'm afraid I have absolutely no idea what that means :( However, my caree has been on aripiprazole - to "augment" mirtazapine, whatever that may...
...was improving on it. I have progressive non-HLA-C*07:04, non-HLA-DQB1*03:03 ME/CFS. My main symptoms are fatigue and cognitive and sleep...
Ponting threads https://www.s4me.info/threads/significant-association-of-dna-variants-with-self-reported-me-cfs-chris-ponting-blog.5520/...
...tagged by the alleles HLA-C*07:04 (OR 2.1 [95% CI 1.4–3.1]) and HLA-DQB1*03:03 (OR 1.5 [95% CI 1.1–2.0]). These alleles were carried by 7.7%...
...study are the people positive for the alleles HLA-C*07:04 and HLA-DQB1*03:03. These folks might be the only people with true ME/CFS, as there...
OK, about the alleles. 10 patients had HLA-DQB1*03:03 4 patients had HLA-C*07:04 12 patients had either DQB1 and/or C Which means that 2...
"Ten of the 12 patients (83.3%) positive for HLA alleles DQB1*03:03 and/or C*07:04 had a response, compared to 12 out of 28 patients (42.9%)...
Finally published!!!!!!! How do I test if I have this? HLA-DQB1*03:03 and/or HLA-C*07:04
...of 22 responders) were still in remission. Patients positive for HLA-DQB1*03:03 and/or HLA-C*07:04 (n = 12) had significantly higher response...
...Here are the stats: HLA-C*07:04 (OR 2.1 [95% CI 1.4–3.1]) HLA-DQB1*03:03 (OR 1.5 [95% CI 1.1–2.0]) OR is odds ratio (chance of having it as a...
Thanks for this. Where is the HLA/antigen image from? I didn't see it in the publication.
...One was tagged by the allele C*07:04 and the other was tagged by HLA-DQB1*03:03. C*07:04 is a class I HLA which presents to killer T cells...
Yes, if the association is confirmed it will indicate that somewhere along the long presentation of antigen to helper CD4 T cells is involved and...
Is it right to say that assuming the HLA-DQB1 association is true, it would mean that the disease process in ME/CFS at least in some patients...
You will have two copies of the DQB1 gene, one on each of your two chromosome 6s, so you might be 02/03:03 or 02/02.
If I have DQB1*02 does it mean I can't have DQB1*03:03 or are they two different things?
Open access, https://www.frontiersin.org/articles/10.3389/fimmu.2019.02715/full Press release,...
Separate names with a comma.