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It's a not a perfect study. The chronically unwell cohorts were not well characterised, and neither were the controls. There was thinking about t-cell activation from latent infections back then: So, only 5 of the 14 people who had rickettsia DNA in their blood were recorded as positive...

I've posted about this old paper before, but I think the detail must have been on Phoenix Rising. I wasn't in this study, but I have tested positive to rickettsias.

Abstract Background: Some investigators believe that a proportion of chronically unwell patients, many with fatigue, have an underlying rickettsial disease. Aim: To investigate the prevalence of markers of rickettsial infection in patients with chronic illnesses. Design: Observational study...

Miami didn't initially register on my mental map of CFS psychobabble. Michael H. Antoni seems likely to be the supervisor of this student. He appears to have been promoting cognitive behavioural therapy for people with cancer, HIV, and CFS for some time. e.g. What's most interesting with his...

A video on the topic of appropriate images has been moved here: Improving images used to depict ME/CFS That thread also has discussion on the topic of images of ME/CFS.

Doxycycline is used for malaria prophylaxis e.g. this is from the CDC: So prospective travellers can probably get it prescribed in most countries. Not that I'm recommending it. The CDC says pregnant women shouldn't take it. If anyone has tablets and decides to take them, be careful to take...

There are a few typos in the paper. Unless I have misunderstood, I think this was the most consequential one I saw - the cPS reduced the time until cascade initiation or fibrin deposition, or it increased the speed of these things. See Figure 2 On the particle size: There's also a platelet...

They seem to present the 'relatively low-shear environment' and lack of endothelial cells of the TEG as a good thing for experimentation, but of course it is a limitation of the study (and would also be a limitation of any experimentation with ME/CFS blood) in terms of knowing what actually...

There were controls. Thromboelastography - looks like there is a special machine to measure relevant blood clotting parameters. I'm not sure what temperature the blood is at when the microplastics are added and the evaluation is done. It could be interesting to compare ME/CFS, LC and control...

On whether microplastics get into blood: (yes, they do)

Label on the article: On the panel is a chiropractor. Dr Mele's qualifications to be giving advice on "chronic fatigue syndrome'? LaSalle University: Master's degree, Religious Education Boston College: BA, English, Psychology Widener University: Psy.D, Clinical Psychology Center for Creative...

Yeah, the nincompoops were always there, it's just that they now have Tik Tok et al to gibber on.

As far as I can understand it, there was a plan by BPS proponents to analyse individual patient data in CFS exercise trials, as a Cochrane review. That horrific idea was headed off during the peer review of the protocol (thanks to those involved in that. Am I correct in assuming that this was...

So, it's definitely not a Cochrane review? I suspect it will give a fairly good impression of one. The protocol mentions using the Cochrane database and using Cochrane tools. It's not clear from the protocol what the definition of 'CFS' is. The 'condition' mentions a main symptom of...

Wow, that Bob Montgomery wikipedia entry link in your post is almost incredible, President of The Australian Psychological Society and all.

I've never understood the premise of being aware of heart beats. The BPS people seem to think that being aware of your heart beats is a good thing, an example of interception, at the same time as saying that people with FND are pathologically aware of bodily sensations and are too...

On the finding that physical impact seems to increase cf-DNA (whereas an increased heart rate does not) Could this, together with the finding that an increased body temperature increases cf-DNA, be why some people with ME/CFS prefer swimming over other exercising - less impact and less...

As @MSEsperanza noted, positivity was relative to the mean of healthy individuals. There isn't any further detail given in this paper but the 2015 paper talks about the 73 healthy controls that were used to create the reference level. Autoimmune autonomic ganglionopathy: an update on diagnosis...

Just noting 68 patients attending the clinic appear to have been diagnosed with FNSD/CD. 9 of these had other conditions that surely might have produced some movement (this includes weakness) or sensory symptoms (this includes pain), I mean "chronic inflammatory demyelinating polyneuropathy"...

Yet again we find people who use the FND label tripping over themselves. 'These are neurological disorders, but because we don't know what's causing them, they are generally considered a psychological disorder'. God of the gaps, the bin for stuff that's too hard. I think more accurately, it's...