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Abstract Background It is generally accepted that endothelial cells (ECs), primarily rely on glycolysis for ATP production, despite having functional mitochondria. However, it is also known that ECs are heterogeneous, and their phenotypic features depend on the vascular bed. Emerging evidence...

His relative or this, UK Government ME/CFS Delivery Plan (includes Attitudes and Education Working Group and Living with ME Working Group) and consultation?

My, effort limited, reaction to Nath's continued whinging is probably best not said. I didn't hold out much hope for the intramural study before they published; I've now lost all hope that NIH intend dealing with ME/CFS in any serious way.

Link to study thread, UK: Investigating the presence of Micro Clots and other blood factors in people with ME/CFS, Sheffield, Caroline Dalton

I believe the stated reason was that it would hinder the chances of it being published in a more notable journal than would happen if they published a preprint.

Blog from @Simon M about this work with a focus on the non-clot aspects. Researchers hunting for ‘something in the blood’ of people with ME "Several small and quite different ME/CFS studies have come up with the same tantalising finding – and now a team of two very talented resarchers, one a...

"When will we get a sterilizing Covid vaccine?" Most likely well before Cochrane take any positive action on their review of exercise for CFS....

Yes, but it is distinct from, for example, the MRC or NIHR who more commonly fund (the currently inadequate levels of) ME/CFS research.

Published papers thread for w/c 29th April. Facebook: https://www.facebook.com/sci4me/posts/pfbid0hCSc3tVQTve3KJyuUwRwKMiFDkFSKSeBLeHdRz13ZMbEKmm4Q8mQ4Dk5969udDBVl Mastodon: https://med-mastodon.com/@s4me/112393118917887840

That is an Innovate UK grant, main thread here, £622,000 grant to improve diagnosis and treatment for ME/CFS and Long Covid

Full title: Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome Abstract Objective: To observe the effects of Qiye Shen'an Pian combined with ghrelin and vitamin B1 on the fatigue...

News in Brief post for w/c 29th April. Facebook: https://www.facebook.com/sci4me/posts/pfbid02cEzvAmrDtEXku1Z2R5znp3qYGsbBydNxDQGak2KrzskxBn3A1XMU5dr2y2XH9fMal Mastodon: https://med-mastodon.com/@s4me/112387568793223847

Abstract TFEB is a master regulator of autophagy, lysosome biogenesis, mitochondrial metabolism, and immunity that works primarily through transcription controlled by cytosol-to-nuclear translocation. Emerging data indicate additional regulatory interactions at the surface of organelles such as...

Link to full Times article with Sajid Javid here, https://archive.ph/2024.05.02-150141/https://www.thetimes.co.uk/article/sajid-javid-patients-with-me-are-being-dismissed-by-doctors-twp2xhs5n Source: The second one is from last year - originally posted here, UK Government ME/CFS Delivery Plan...

For reference. "We use the term PSS here also because it is the preferred umbrella term by people living with symptoms [3]," ref 3 is to The Most Popular Terms for Medically Unexplained Symptoms: The Views of CFS Patients, 2015, Picariello et al "During clinical consultations, people with PSS...

Highlights Interplay between HIF-1 mitochondria and ROS stand at the forefront of cardiac diseases Depending on the hypoxic stress, HIF-1 deciphers a paradoxical response that deserves to be deeply investigated The exploration of the “HIF-1 and mitochondria” crosstalk will open new avenues...

Discussion CFS patients often feel distressed due to fatigue, joint pain, low sleep quality, and low mood.[51] At present, Western medicine is unable to explain the cause of this disease. However, from the perspective of traditional Chinese medicine, we believe that there are three causes of...

Abstract Background: Chronic fatigue syndrome (CFS) is a long-term and complex chronic disease that seriously affects the physical and mental health and quality of life of patients. Massage, as one of the methods in traditional Chinese medicine, can treat both symptoms and root causes and is...

Could be worth those in touch with him highlighting this to George Monbiot, he may well find the connection interesting.

Link to current campaign, https://crowdfund.berkeley.edu/project/42302 $3,747 donated, 5% of total, 29 days remaining.