1. Sign our petition calling on Cochrane to withdraw their review of Exercise Therapy for 'CFS'.
    Dismiss Notice
  2. Guest, the 'News in Brief' for the week beginning 3rd March 2025 is here.
    Dismiss Notice
  3. Welcome! Read the Core Purpose and Values of our forum.
    Dismiss Notice

Search Results

Search Again
Page 1 of 42
  1. wigglethemouse
    Post

    What do you think needs to be tested in the blood (plasma, PBMCs, etc) of patients?

    I seem to remember Lipkin and Morten metabolomic studies identified important unknown metabolites. I'm wondering if it's possible to replicate the...
    Post by: wigglethemouse, Jan 31, 2025 in forum: Laboratory and genetic testing, medical imaging
  2. wigglethemouse
    Post

    Costochondritis and chest and rib pain

    Yes, occasionally I can find the spot and when I press on it I feel the pain.
    Post by: wigglethemouse, Jan 17, 2025 in forum: Pain and Inflammation
  3. wigglethemouse
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    According to Genecards WASF3 is a member of the WAS family of proteins. WASF3 was highlighted by the NIH study. Could this be relevant if there is...
    Post by: wigglethemouse, Jan 16, 2025 in forum: ME/CFS research
  4. wigglethemouse
    Post

    Costochondritis and chest and rib pain

    Copied post Just wanted to say I agree with what you say about the chest pain / chostochondritis. I get it too as you describe. Thank you for...
    Post by: wigglethemouse, Jan 16, 2025 in forum: Pain and Inflammation
  5. wigglethemouse
    Post

    Review Machine learning and multi-omics in precision medicine for ME/CFS, 2025, Huang....Armstrong

    Just wanted to say I agree with what you say about the chest pain / chostochondritis. I get it too as you describe. Thank you for mentioning it....
    Post by: wigglethemouse, Jan 16, 2025 in forum: ME/CFS research
  6. wigglethemouse
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    In case it is helpful to someone there seems to be quite a few COVID studies that have highlighted IGHV3–30 in spike neutralising antibodies. Here...
    Post by: wigglethemouse, Jan 16, 2025 in forum: ME/CFS research
  7. wigglethemouse
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    The acknowledgement section of the paper states the data is available. Here is the link - click on (more) to see the links to the actual data....
    Post by: wigglethemouse, Jan 16, 2025 in forum: ME/CFS research
  8. wigglethemouse
    Post

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    I was about to ask the same thing. So this paper is the second replication of the IGHV3-30 finding, with different methods being used. This is a...
    Post by: wigglethemouse, Jan 15, 2025 in forum: ME/CFS research
  9. wigglethemouse
    Post

    Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Iu, Hanson et al

    Shout out to @forestglip who posted a Cornell Chronicle news article in the NIH news thread that describes this work in laymans terms....
    Post by: wigglethemouse, Jan 15, 2025 in forum: ME/CFS research
  10. wigglethemouse
    Post

    SARS-CoV-2 Viral Load and Cytokine Dynamics Profile as Early Signatures of Long COVID Condition in Hospitalized Individuals, 2025, Domínguez et al.

    Interesting that CXCL10 = IP-10 has been highlighted in several other Long Covid threads. https://www.s4me.info/search/36265054/?q=cxcl10&o=date
    Post by: wigglethemouse, Jan 14, 2025 in forum: Long Covid research
  11. wigglethemouse
    Post

    Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Iu, Hanson et al

    This video at 6hrs:27min to 6hrs:33min is interesting. Dr Hanson describes the teams work on CD8 T-cells that have been exposed to an antigen not...
    Post by: wigglethemouse, Jan 14, 2025 in forum: ME/CFS research
  12. wigglethemouse
    Post

    What do we mean by a diagnosis like ME/CFS?

    This is some of what I was referring too about a lack of changes observed after exercise possibly leading to PEM. I seem to remember...
    Post by: wigglethemouse, Jan 14, 2025 in forum: Diagnostic Criteria and Naming Discussions
  13. wigglethemouse
    Post

    What do we mean by a diagnosis like ME/CFS?

    This thread is interesting and makes you think about ME/CFS in a different way. Would it be helpful to revisit the few PEM induction studies that...
    Post by: wigglethemouse, Jan 13, 2025 in forum: Diagnostic Criteria and Naming Discussions
  14. wigglethemouse
    Post

    Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank, 2024, Huang et al

    They found 1/4 of people with ME/CFS had hypertension as did 1/4 of the people in the Comparison group. [ATTACH] I've been led to believe for...
    Post by: wigglethemouse, Nov 29, 2024 in forum: ME/CFS research
  15. wigglethemouse
    Post

    Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank, 2024, Huang et al

    I was struck by the fact that hypertension was reported as present in 24% of those with ME/CFS and 26% of Control - no statistical difference. Yet...
    Post by: wigglethemouse, Nov 29, 2024 in forum: ME/CFS research
  16. wigglethemouse
    Post

    Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank, 2024, Huang et al

    @MelbME : The paper sticks to facts and not hypothesis about mechanisms (quite rightly). Can you comment on the hypothetical - do the findings in...
    Post by: wigglethemouse, Nov 29, 2024 in forum: ME/CFS research
  17. wigglethemouse
    Post

    Why so little focus on Functional Disability and so much focus on “Symptoms”?

    One aspect of PEM is the delay before it appears, with a timeframe roughly 12-48 hours. How many things in the body have a delay like this, and...
    Post by: wigglethemouse, Nov 28, 2024 in forum: Other research methodology topics
  18. wigglethemouse
    Post

    Trial Report RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2024, Cash et al

    As a sanity check here is the result of a twitter survey from 2022 that obviously has self bias in the reporting and it looks like on average...
    Post by: wigglethemouse, Nov 27, 2024 in forum: ME/CFS research
  19. wigglethemouse
    Post

    Trial Report RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2024, Cash et al

    Here is the registration for this study for people that wat to look at the registered protocol. https://clinicaltrials.gov/study/NCT05273372 The...
    Post by: wigglethemouse, Nov 27, 2024 in forum: ME/CFS research
  20. wigglethemouse
    Post

    Trial Report RESTORE ME: A RCT of Oxaloacetate for Improving Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2024, Cash et al

    I don't like to read the twaddle. Straight to the graphs. According to this the treatment was non-significant. The graph on the right looks like...
    Post by: wigglethemouse, Nov 27, 2024 in forum: ME/CFS research
Showing results 1 to 20 of 822 Next >
Search Again
Page 1 of 42