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Fortunately, CRISPR/Cas13 could serve as diagnostic tool as well.

2021 paper Abstract A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses Xueqiu Lin 1,6, Yanxia Liu 1,6,7, Augustine Chemparathy 1,2,6, Tara Pande 3, Marie La Russa 1,7, Lei S Qi 1,4,5,7,8,∗ The coronavirus disease 2019 (COVID-19) pandemic caused...

Would the NIH consider performing same psychology based testing on cancer patients after receiving chemotherapy. Would they make the same argument that cancer patients are exhibiting avoidance behavior?

As a participant in the study I can tell you that I told Dr Wallit and his staff that I was already in PEM from traveling to Bethesda by plane. They probably overlooked the fact that I could barely hold my head up as I was answering their questions. My PEM became so severe I could not complete...

I sent my first muscle biopsy years ago to Baylor for viral testing. It didn’t turn up anything. Local pathologist looked for red ragged fibers. Nothing to explain the constant chronic pain in my legs and random widespread muscle fasciculations. A sports medicine doctor utilized an algorithm...

I asked the NIH specifically about whether muscle biopsies where going to be tested like the immune cells on Seahorse machine. Due to limitations of the Seahorse analyzer, individual muscle cells could not be separated and analyzed like free floating immune cells. So we do not know whether the...

I caught parts of 2 day presentation on biology of fatigue when it first aired but I was able to watch day 1 in more detail this morning. I was particularly interested in Asya Rolls PhD presentation regarding brain immune interactions - how parts of the brain such as the insular cortex perceive...

I think it would be beneficial for Dr Nath to discuss a protocol of testing that suspected MECFS patients should undergo to rule out other serious conditions. NIH could collaborate with a clinical center like the Bateman Horne center and help educate clinicians on how to perform a thorough...

I suspect our best hope is that as they study new onset LC, it will shed light on how post viral syndromes are triggered and then become chronic. I am not optimistic that MECFS will get more funding on it's own. I wonder if Dr David Systrom at Brigham hospital is getting involved in LC...

In general, I find these discussions and preliminary findings encouraging and very frustrating at the same time. The most significant findings seem to be related to metabolic studies performed on immune cells using Seahorse and other immunologic alterations such as unexplained B cell clonal...

It would be helpful if the exact methods used for evaluating NK cell activity were clearly described.

I am glad to hear that results/analysis of the intramural study at NIH are finally forthcoming. It has been over 5 years since my second trip to the clinical center at Bethesda. I am curious to see if the NIH fMRI component of their study replicated Dr Rayhan’s findings. Several webinar...