Long-term health impacts of COVID-19 among 242,712 adults in England Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have recovered from COVID-19. Overall, 276,840/800,000 (34·6%) of invited participants took part. Mental health and health-related quality of life were worse among participants with ongoing persistent symptoms post-COVID compared with those who had never had COVID-19 or had recovered. In this study, median duration of COVID-related symptoms (N = 130,251) was 1·3 weeks (inter-quartile range 6 days to 2 weeks), with 7·5% and 5·2% reporting ongoing symptoms ≥12 weeks and ≥52 weeks respectively. Female sex, ≥1 comorbidity and being infected when Wild-type variant was dominant were associated with higher probability of symptoms lasting ≥12 weeks and longer recovery time in those with persistent symptoms. Although COVID-19 is usually of short duration, some adults experience persistent and burdensome illness. https://www.nature.com/articles/s41467-023-41879-2
"Participants with ongoing symptoms lasting ≥12 weeks following COVID-19 reported worse current health, including a higher number of symptoms within the last two weeks, and greater reduction in ability to carry out daily activities due to these symptoms (Table 2). Post-exertional malaise, characterised by asking respondents who reported fatigue about worsening of fatigue symptoms after minimal physical and mental effort, and whether exercise makes fatigue symptoms worse, was also more common in individuals reporting ongoing persistent symptoms" Lucibee has posted about this aspect on Twitter The authors claim that they use the validated DePaul Symptom Questionnaire but only use three questions from it.....
