Short-term microgravity effects simulation doesn't affect fNIRS measures of cerebral oxygenation changes induced by cognitive load, 2025, Peysakhovich

In summary, the findings demonstrated that increasing difficulty levels in the cognitive task resulted in reduced accuracy, prolonged response times, and increased perceived difficulty scores. Task performance remained unaffected by the inclination levels. Additionally, the results revealed an increase in oxygenated hemoglobin (HbO) and a decrease in deoxygenated hemoglobin (HbR) concentrations with task difficulty, and these trends were not influenced by the head-down tilt angles.

These encouraging results suggest that fNIRS measures can serve as a reliable indicator of cognitive load in microgravity conditions without the need for correction due to cephalic fluid shift.
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