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What is the difference between Rituximab and Daratumumab?

Was told once by a senior researcher in materials science that when he gets a paper to read he goes straight to the methodology section, and doesn't read the full paper until he knows it is worth reading. Said it saved him a lot of time.

Indeed. The best way to clear muddied waters is to stop stirring it up.

A very tightly circled bunch of wagons indeed.

"Adjustments by Open-OH:An SBRI follow-on funding to develop an evidence based interventions [sic] for Mental Health." Anybody need more evidence about what is really happening here? It is beyond clear that the government still happy to treat ME/CFS, et al, as a psycho-behavioural problem, to...

Dr. Jason Busse has established multiple connections to the insurance industry through his clinical practice, research, and advisory roles: Enough said. :grumpy::thumbsdown:

After more than 40 years of dealing with it all I still don't know what to say when somebody says 'you are looking good/well', when in reality I can barely stand and am heading directly home to crash. :confused:

That makes a lot of sense. Might explain why – at least for me – getting into action is hard, but continuing it at least somewhat easier, leading to both appearing (relatively & temporarily) normal once moving, and also easily over estimating how much I really can continue the activity without...

I have not lost strength, beyond normal expected for my age (early 60s). I have lost stamina, and nothing I have tried brings it back. There is a hard ceiling. It would not be surprising if some deconditioning was going on for some patients, mainly at the severe-very severe end of the spectrum...

Wasn't there some work published in the last 6-12 months showing that the additional benefit of updated vaccinations for Covid was becoming less with each generation of vaccine? Something about the immune response was becoming less and fading faster? Don't know if that is normal pattern for...

Be careful using the term 'unmanaged', as that gets used to open the door to claims that 'managed (i.e. treated)' patients do better. I take your point, just suggesting be careful about how you phrase it.

Absolutely this.

I have little doubt that one day the real story will come to the fore, more or less. But also have little doubt that for the victims, or their surviving loved ones, it will be cold comfort. Just way too little, way too late.

Some years back the wife of a friend of mine was having all sorts of health troubles, and was bundled off to the psychs. Long story short, eventually somebody did some appropriate (and standard, widely available) testing and it came back positive for a specific and well known gland problem...

Not sure that is where the problem lies.

This is the most important point about the political angle in ME/CFS: the BPS club could not have got away with it, for so long, and continue to do so, without the sustained support and protection from the rest of the power and governance structure. Which is a huge chunk of the reason those...

In what universe is this even internally consistent?

In fairness to the modern healthcare system, that probably catches the vast bulk of known and (more-or-less) understood serious problems. Not so well known and understood, on the other hand.... This. Though there is the issue of how well doctors and researchers are using existing knowledge...

This.

Which is exactly the sort of professional irresponsibility and cowardice that has allowed this shitfest to go for so long.