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    UK:ME Association funds research for a new clinical assessment toolkit in NHS ME/CFS specialist services, 2023

    That makes no sense. You can't tell how well a questionnaire is picking up changes unless you have another way of measuring the changes. It's like sticking a thermometer into water at different times and saying 'this will tell us the temperature of the water, and also whether our thermometer is...
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    Functional Neurological Disorders: Challenging the Mainstream Agnostic Causative Position 2024 Scamvougeras and Castle

    That reminded me of this: https://www.newscientist.com/article/dn17064-quack-remedies-spread-by-virtue-of-being-useless/
  3. E

    UK:NHS: Feel Good Tennis for Long Covid

    Week 1: 'Understanding Long Covid' and 'Symptom Recognition'. As long as those symptoms don't include 'being too ill to play tennis'.
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    OpenAi's new ChatGPT

    Text generators in a nutshell. Great if you want a squishily averaged synthesis of general opinion. Not great if you want factual accuracy - though it can look like it if you're asking about a topic where fact and general opinion happen to more or less overlap.
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    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I feel sad for the kids who underwent that testing presumably in the hope that they were contributing to some meaningful research.
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    The Effect of Physiotherapy on Dyspnea, Muscle Strength and Functional Status in Patients with Long COVID Syndrome 2024 Michalas et al

    In the Discussion they say "The main limitation is the small sample size. Beyond the participants’ willingness, difficult transportation to the hospital and a pessimistic view of the benefits of rehabilitation played a significant role in participants’ decision to take part or not. It has long...
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    The Effect of Physiotherapy on Dyspnea, Muscle Strength and Functional Status in Patients with Long COVID Syndrome 2024 Michalas et al

    When the lack of statistically significant differences between the exercise group and control group is so glaring that all you can put under Conclusions is 'Similar studies have reported...'
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    Review Prevalence of mental health conditions and brain fog in people with long COVID, 2024, van der Feltz-Cornelis et al

    Not convinced that lumping 'mental health conditions' and 'brain fog' together tells us much about either category of problem.
  9. E

    BBC: Long Covid course [LP] is ‘exploiting people’, says ex-GB rower, 2024, article and radio program

    It's quite telling that she said that as if it meant LC is all in the mind, whereas if you have fatigue/pain + dyautonomia + brainfog then of course it's easier to walk around in a familiar space with short distances between easily accessible resting spots than it is to walk outside where there...
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    UniteToFight2024 Long Covid and ME/CFS conference, 15th and 16th May 2024

    Maybe when the transcript becomes available it'll shed some light.
  11. E

    A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection, 2024, Singh et al.

    Can't believe they let the mice read that article by George Monbiot.
  12. E

    UniteToFight2024 Long Covid and ME/CFS conference, 15th and 16th May 2024

    From the first page of selected quotes: "It appears that about 50% patients have both MS and ME/CFS" - Prof. Dr. Ron Davis ??
  13. E

    Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue, 2024, Hosp et al

    "the time span between positive SARS-CoV-2 PCR and the cerebral MRI did not explain alterations of gray matter DMI parameters or spatial distribution of V-extra changes between the PCC and UPC groups. Thus, one could speculate on a slow or even non-reversibility of microstructural changes...
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    Changes in interoceptive accuracy related to emotional interference in somatic symptom disorder, 2024, Lee et al

    Small sample, "no significant difference in the absolute values of IA between patients with SSD and healthy controls, regardless of the condition". It's just statistical noise. If they'd done it on another day they might have got results that went the opposite way (more interference with...
  15. E

    United Kingdom: News from BACME - British Association of Clinicians in ME/CFS

    In contrast, from the DecodeME transcript above: :emoji_clap:
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    Muscle abnormalities worsen after post-exertional malaise in long COVID, 2023/4, Wüst, van Vugt, Appelman et al

    "#Longcovid related #PEM question: do female patients experience PEM symptoms that align with the menstrual cycle?" In my case, in 2.5 years of long Covid: no.
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    Trial Report Examining well-being and cognitive function in people with long Covid and ME/CFS, and age-matched healthy controls, 2024, Sanal-Hayes

    The Cognitron/GBIT study found measurable, significant post-Covid cognitive impairment with more than 100,000 participants (and that didn't even include a more severe cohort). These researchers trying to say they've disproved that on the basis of 50 people doing a Stroop test is just sad.
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    Trial Report Examining well-being and cognitive function in people with long Covid and ME/CFS, and age-matched healthy controls, 2024, Sanal-Hayes

    "Long COVID and ME/CFS cause impaired well-being and cognitive function", but "People with Long COVID and ME/CFS have... comparable cognitive function when compared to controls" and "Our cognitive function findings do not support the existing literature that suggest cognitive impairment...
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    Resources on why the Name “CFS” is problematic and “ME” or “ME/CFS” is recommended.

    It's not actually citing any of the sources directly, it's just generating text that looks as if it does, because those sources are somewhere in the training data that gives it its probabilities for each word following the previous one. That's why it lists five "citations" but only 1, 3 and 4...
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    Protocol Trial registration: Low-dose Naltrexone for Post-COVID Fatigue Syndrome, 2022, Luis Nacul, British Columbia Women's Hospital & Health Centre

    That was my thought too. Especially as it takes several weeks just to work up to the full dose.
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