Interesting that muscles are considered to be deconditioned when that's the explanation being offered for a person's disabled state, but the same muscles are considered to be working normally when we're talking about "effort preference" and "mismatch between what someone thinks they can achieve...
Supplementary Information p. 52, discussing the cardiopulmonary exercise test: "Effort preference did not correlate with peak power in PI-ME/CFS participants (r(6)=0.13, p=0.8) which suggests that effort preference did not impact CPET performance, perhaps related to experimental incentives to...
He thinks the brain of the ME patient has assessed their muscles as less capable than they actually are (that's his "mismatch between what someone thinks they can achieve and what their bodies perform"), so it sets a lower goal at the start of the strength task than a healthily functioning brain...
From the Discussion section:
"Patients with long COVID had elevated levels of IL-8, GFAP and TGFβ, with TGFβ specifically increased in the cohort with brain fog. GFAP is a robust marker of cerebrovascular damage and is elevated after repetitive head trauma, reflecting BBB disruption, as seen in...
This caught my eye in the Supplementary Information, pp. 9-10:
"Motivation was assessed using the Effort-Expenditure for Rewards Task (EEfRT) which assesses effort, fatigue, and reward sensitivity (Figure S5A) [...] multiple models were evaluated to assess for group differences and assess for...
I'm afraid the psychobabblers will just pick out the phrase about "choosing to exert effort" and say "See, they just need to learn to make more effort!"
The neurologist who tried to diagnose my Long Covid cognitive impairment and dysautonomia as FND was entirely open about it. "This is FND: what we used to call conversion disorder." Then he told me to "see a shrink".
Luckily I knew enough by then to laugh it off, but who knows how many other...
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