Continuity. It would need somewhere where the data can be stored, and people to process any application and distribute the data. At the moment it is stored on servers at the University of Edinburgh, there is a data access committee to review applications, and UoE staff who can process successful...
Abstract
Background
Individuals with prolonged symptoms after a mild traumatic brain injury (mTBI) report requiring more effort to complete complex and sustained activities. However, the relationship between cognitive workload and patient-reported symptoms is unclear.
Objective
To compare the...
Highlights
• Functional cognitive disorder can occur comorbidly with Alzheimer's disease.
• Clinical clues may identify patients at risk of converting to Alzheimer's disease.
• This study has implications for management, prognosis and research trials.
• We propose potential mechanisms which may...
Abstract
Background
Deficits in emotional awareness may contribute to the development and maintenance of somatic symptoms. This study explored emotional awareness deficits and their association with somatic symptoms among individuals with a high somatic symptom burden from an online community...
Abstract
Epstein-Barr Virus (EBV) is an endemic herpesvirus implicated in autoimmunity, cancer, and neurological disorders. Though primary infection typically resolves with subclinical symptoms, long-term complications can arise due to immune dysregulation or viral latency, in which EBV DNA is...
Highlights
• Individuals with fibromyalgia require higher incentives for physical effort tasks.
• No differences in cognitive effort task between fibromyalgia and control groups.
• Fibromyalgia participants display increased willingness to wait for rewards.
• This suggests higher...
"Our findings reveal that the most frequently reported psychosomatic symptoms are fatigue, back pain, a bloated stomach, and headaches. These physical symptoms often lie at the intersection of psychological and somatic factors, which largely accounts for the manifestation of psychosomatization...
"In essence, fatigue, back pain, a bloated stomach, and headaches appear to be psychosomatic symptoms that frequently manifest, often in combination. This suggests that special attention should be paid to such symptom clusters during differential diagnosis, since, as Wise (1) explains...
The primary objective of this study was to examine the relationship between personal variables, as measured by the NEO-PI-R, and psychosomatic symptoms, assessed through the PSS, from a neuropsychological perspective. The secondary aim was to evaluate the frequency of various psychosomatic...
"A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
These include:
asthma
chronic obstructive pulmonary disorder
inflammatory bowel disease
Chronic inflammation-related diseases have been...
Abstract
Objectives
To evaluate the frequency and number of vulnerability factors for the development of pain-predominant disorders of gut–brain interaction (p-DGBI) in a well-defined cohort of pediatric patients and examine associations with pain severity and functional impairment.
Methods...
Full title: Myasthenia gravis with antibodies against the AChR, current knowledge on pathophysiology and an update on treatment strategies with special focus on targeting plasma cells
Highlights
• Thymic involution, follicular hyperplasia and thymoma observed in AChR-MG are associated with...
Highlights
The BDS checklist score was negatively associated with autonomic arousal.
Individuals with FSD, especially multi-organ, had faster heart rates, independent of sex, age, smoking, and activity.
An increased sympathetic neural and neurohormonal activity in patients with FSD may be...
Abstract
Objectives:
Fatigue is the main symptom of primary biliary cholangitis (PBC), but has not yet been improved by any therapeutic intervention. This study evaluated the efficacy and safety of hypnosis and psychoeducation in improving fatigue associated with PBC (PBC-HOPE ClinicalTrial.gov...
Full abstract.
ABSTRACT
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and often misunderstood illness, characterized by post-exertional malaise, unrefreshing sleep, and cognitive impairments.
Objective
To investigate how question phrasing in ME/CFS...
Selected quotes.
"While FCD may present in isolation, it is often part of a broader syndrome such as fibromyalgia or chronic fatigue syndrome.5,6"
"Intervention
Mementum was designed as a self-help app supporting the delivery of education about predisposing, precipitating and maintaining...
Abstract
Functional cognitive disorder is the cognitive subtype of functional neurological disorders. Symptoms are associated with a high level of distress and typically arise due to various risk factors including abnormal focused attention, high memory expectations and poor metacognition...
"According to the scientific literature, DB patterns might be harmful, self-perpetuating patterns [14,20] and may partially explain some MUPS [18,21,22]. There are indications that its correction after breathing therapy combined with stress reduction and lifestyle management is associated with...
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