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This is much better for me! (Except the two rightmost columns which are still problematic. Could they be a different colour entirely? Lilac or something like that.) The red is still a bit too intense - paler or darker would be better for me. There's an effect when blue and red are beside...

You're very kind. For me, making the white less white and the colours less bright would help. Pastels are good. Darker shades can also work eg navy instead of blue, burgundy instead of red, depending on what other colours are there. But I wouldn't waste much of your energy on it, certainly...

Great graph. Am sure I'm not the only one with this problem: I find charts/graphs really difficult to look at now. My brain seems to get dazzled by strong contrasts in colour. I find it difficult to look at stripes, dotted patterns (tiny dots can be OK)...geometric patterns are the worst...

And from the discussion (Reddy 2015, https://academic.oup.com/schizophreniabulletin/article/41/5/1045/1921437?login=false#83746476):

Great find, @bobbler . Right off the bat we have what may be the dealbreaker - Treadway recommended individual calibration of what constitutes a hard task in this schizophrenia study: If I'm repeating things others have already said, oops. My individual calibration for S4ME is lower than...

And in the protocol paper itself AM is described differently to in the documents @Lucibee quoted:

So the protocol described AM as essentially graded cognitive therapy, but in this paper they describe AM as a more general graded activity therapy, including both cognitive and physical activity:

I love this kind of discussion, where people are thinking and sharing and honing and finally figuring it out. So here's a summary of some of the key observations that moved it forward: Bobbler & Simon M start spotting the real problem: Sam Carter spots what healthy volunteer F is doing...

PS My interpretation on first skim does not, of course, make sense given that earlier in the same paragraph they say this: But still, readers have limits and biases and I'm not sure how many would go, hm, I'll check out the method.

I agree completely. I have to say I missed the corresponding part in the results section when I read the paper, because the results section is above the methods. So when I read this, I thought "complete" meant "chose": It's only in the methods section that it is made clear that "complete"...

Yes, someone posted in the early pages of the thread that they had heard UCSF (I presume that's University of California at San Francisco?) was considering a trial. Hopefully any universities considering trials might dig a bit deeper first rather than launching straight in - and they may have...

I am unwisely logging on despite my need to not click buttons (so a pain flare will go down) because I think your point is absolutely key and needs to be amplified. If you're not successful at completing the hard tasks, then it would be illogical to keep attempting them. Because this changes...

I hear you. I've been quiet for a couple of days because pain flared due to...repetitive prolonged button pressing. The irony. This happens when I play around with data, because my body can't handle the sustained pressing of the CTRL button and the down arrow. Or rather, it builds over a few...

I think it would be most compelling to demonstrate the issue with the Effort task with data - people might find the logic of it hard to follow. If it can be shown from the data that the difference in the hard:easy ratio between patients and controls could be due to something else - specifically...

There are supplementary figures labelled S1, S2 etc in the Supplementary Information file. So the source data has data for figures 1-9 from the published paper, and S1-S20 from the Supplementary Information file.

Addendum: The 17.6% HVs with excessive tachy on this test would not be considered to have POTS. Some will have other reasons for that tachy eg a cardiac issue. They can see from the pattern of what happens when whether it's POTS or some other issue.

They don't say that 40% have excessive orthostatic tachycardia. They say that 3/17 (17.6%) HVs had that. 7/17 (41%) HVs had symptoms - this would be any symptom at all reported during the head-up tilt test, which could be unconnected with the test, or they may have only counted prodromal...

Absolutely. I think we can't know what exactly is happening here. My interpretation of what's most likely to be happening is that Walitt, as first author, was in charge of the wording of the paper and wrote the objectionable (and poorly written) presentation of effort preference in it. I...

There's a known false-positive issue with the head-up tilt test, where people without a history of syncope will faint/test positive. It's a really demanding test that takes away people's ability to do all the things they may do naturally and possibly unwittingly that prevent them from fainting...

Yup. They're tremendously interested on initial assessment, and then they get the negative antibody panel and react like I've sullied their office. I got "This nice psychiatrist will help your recovery" (an immunologist), and then from rheumies: "Take paracetamol before your GET sessions"...