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    Typical Lyme Story, Atypical Victim

    Re-reading it. It's all pretty eye-opening, but one chapter in particular is fascinating. It concerns Operation Mongoose back in 1962. It arguably should be a must read by anyone with more than a passing interest in weaponizing TBDs, and the motivations behind US involvement in ticks and...
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    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Plenty of precedent for this, I suspect. Although not viruses, spirochetes are notoriously adept at making the immune system think they are not there. So it's not as if our immune systems always get it right. Diagnostics don't always help. Testing brings in the overtly human arrogant blunder...
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    A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients, 2020, Morrissette et al

    This is an Aucott product. If memory serves me, isn't he an ex-Infectious-Disease-expert-turned-rheumatologist? Wonder what his emphasis might be. "...there is no biological method to diagnose PTLDS..." Sure there is. There are several. At least three are FDA-approved: Conventional ELISA...
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    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Clearly, CFS is unacceptable. Regardless, do we know definitively that even a majority of people diagnosed with ME/CFS are, in fact, post anything? Do we trust diagnostics, or their assorted protocols, across the board enough to accept a label which by definition states we are cleared of a...
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    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Ah, some one had the presence of mind to avoid embracing "chronic covid". Talk about stigma associated with a simple, single adjective...
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    Does your ME feel like your initial infection?

    More than one infection may be at play, or have triggered what we call ME/CFS. I also had slow and progressive onset comprised primarily of neurological and autonomic symptoms, but had a vicious bout of acute Lyme that intersected roughly five years into that slow descent, and which caused rapid...
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    Unconventional diagnostic tests for Lyme borreliosis: a systematic review, 2019, Raffetin et al.

    I suspect what they are trying to diagnose is Lyme disease. "Chronic" is nothing more than an adjective. Do they use "chronic"? Probably. At one time, pretty much everybody did, even IDSA-types in the US. It's just an adjective. However, it became politicized around the early 1990's, and remains...
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    The Role of Iron Metabolism in Fatigue, Depression, and Quality of Life in Multiple Sclerosis Patients, 2020, Knyszyńska et al

    "Multiple Sclerosis (MS) is a chronic inflammatory disease of autoimmune origin..." Maybe, maybe not. Not an encouraging sign they make such a declaration when the origin debate remains very much in play.
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    Characterization of Post–exertional Malaise in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (2020) Stussman, Nath et al.

    Why word it this way? Why not title it "NIH details patients' experiences with post exertional malaise in ME/CFS"? Perhaps more to the point, why are they still tackling definitions at this stage of the game? Shouldn't they be talking about whether ME/CFS is an immune dysfunction, or...
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    Psychosomatic medicine and the psychologising of physical diseases

    Unless Kant was onto something, and causation is nothing more than perspective, a human "tool" with which to better navigate life. I think that was Kant. Sorry if I am misremembering. Sorry, too, if I am bungling what he or whoever said about causation. As for psychosomatic illnesses, just...
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    Characterization of Post–exertional Malaise in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (2020) Stussman, Nath et al.

    I am delighted whenever the voice of the patient is integrated into medical discovery. Focus groups, however, at least to this old time market researcher, smack of marketing.
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    ..effect of VEGF gene inactivation ... on muscle enzyme activity, capillary supply & endurance exercise, 2020, Breen et al

    I thought a general rule of thumb is pathogens resulted in elevated VEGF, at least as far as serum VEGF (vs CSF VEGF as pertains to one of the first two studies in this thread, not the one I linked to.) Same with cancerous tumors. Low VEGF seemed peculiar to a couple cardiac issues, and a host...
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    ..effect of VEGF gene inactivation ... on muscle enzyme activity, capillary supply & endurance exercise, 2020, Breen et al

    Are they looking at a relevant marker but for the wrong reasons, I wonder...: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300888/
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    Psychiatrists’ Understanding and Management of Conversion Disorder: A Bi-National Survey and Comparison with Neurologists, 2020, Dent et al

    But there seems to me a meanness of spirit underpinning it. People are being harmed, but still this spectacle continues and encouraged and rewarded, like 19th century gentry gathering to hunt fox. It almost has the feel of perdition.
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    Diagnostic pathways of patients consulting at the infectious diseases ward for presumed Lyme disease (preprint), 2020, Lutaud et al

    Yep. They build a mouse trap that, it would appear, in their eyes at least, virtually ensures they catch no person with Lyme, then appear to scratch their heads at delusional patients' beliefs they have Lyme. Is it possible the patients know something these researchers do not? Hard to tell...
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    Diagnostic pathways of patients consulting at the infectious diseases ward for presumed Lyme disease (preprint), 2020, Lutaud et al

    The inclusion criteria are silly, and are predictive of the findings. What does France know about Borrelia other than what the US tells it? If they used the 2T CDC testing to argue no clinical evidence for Lyme, there's more than a fair chance some of these poor souls in fact had/have Lyme...
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    Video: Dr Jack Lambert - Lyme Disease and PoTS

    I'd be interested in knowing what part(s) looks pretty dubious. Anything Lambert is saying in particular, or just the presence of the tweet associated with this Mortem Group? Btw, I am familiar with neither Lambert nor the Mortem Group, but other than the tickplex reference, I found most of...
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    Chronic Lyme Disease: a discussion of the epidemiological data

    Another acute study. Generally speaking, acute and/or early disseminated cases - that are promptly treated - are not the issue. Late stage is. Persistent Lyme. What few potential Late stage patients they recruit appear to me as not having been even confirmed. This is not complicated. Find Late...
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