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  1. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    According to the Spanish newspaper, El País, Patrick Vallance is having serious second thoughts about giving people just one dose and waiting. The UK papers seem a bit more reticent so far.
  2. Jonathan Edwards

    Biologic and Nonbiologic Interventions for Fatigue in Rheumatoid Arthritis (2019). Calabrese.

    It makes things even worse since it is presumably done as part of a money-making process. What shocks me is that thirty years ago no US physician would have bullshitted like this. US medicine used to be rigorous when it came to putting out material. Admittedly in those days it was in textbooks...
  3. Jonathan Edwards

    Biologic and Nonbiologic Interventions for Fatigue in Rheumatoid Arthritis (2019). Calabrese.

    How can my colleagues have become so mindblowingly ignorant? Thirty years ago no US physician would have made themselves look such a fool. What happened to the other six classes of drug that reduce fatigue? What happened to the need for evidence?
  4. Jonathan Edwards

    "Sitting up straight does not prevent or treat back pain, study finds"

    Study with meaningless methodology shows that studies with meaningless methodology cannot be trusted - or does it? I seem to remember that there was a study that showed that people with osteoporosis who did extension spinal exercises had fewer fractures leading to kyphosis, and that those doing...
  5. Jonathan Edwards

    Oxalates may be a problem for people with M.E.

    With due respect, anyone can be an expert and publish. The site does not look like a reliable source of anything. Everyone is entitled to recommend sites but others are also entitled to urge scepticism! The world is full of bogus information just now. This looks like more.
  6. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    I think it is unlikely that if a vaccine reduces symptomatic infection it does not reduce transmission. If you make enough virus to cough around and infect others you almost certainly have made enough virus to feel ill. There is no certainty that the two will match but it would be surprising if...
  7. Jonathan Edwards

    NICE ME/CFS guideline - submissions to the draft guideline consultation, December 2020

    I agree. I am afraid that there are too many unsubstantiated suggestions in this submission - which means it can be dismissed by the committee in its entirely. The S4ME submission is much more balanced and likely to be take seriously, at least by those members of the committee with open minds.
  8. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    Yes, one may be too optimistic and the other too pessimistic. But if a vaccine does not prevent a person growing up enough virus to show up on PCR then it would be disappointing.
  9. Jonathan Edwards

    Trisha Greenhalgh on ME/CFS and Long Covid

    I certainly do not think the webinar should be posted. I suspect all of what Greenhalgh said was ill-informed. What I, and I suspect @Esther12 are asking for is for a transcript to be available in the context of a discussion such as here so that it can be established exactly what was said. It...
  10. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    Yes, it has come out in various news outlets. There is a suggestion that for the vulnerable elderly a single dose of Pfizer vaccine is almost useless or at least gives only a few people protection. It does not surprise me. These vaccines are using new technology and we have no evidence for...
  11. Jonathan Edwards

    The evidence for CBT in any condition, population or context... A meta-review... and panoramic meta-analysis, 2021, Fordham et al.

    That's a very good point. I can think of lots of people with faulty beliefs who seem to do pretty well. Luciano Pavarotti had a faulty belief that he was not a very good singer, for instance.
  12. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    It seems common over here - everyone feels a lot better after the jab, even if they hadn't been feeling ill. I a looking forward to it, although Israel seems to be saying that one dose doesn't work. I will have to make sure I feel better after the second dose.
  13. Jonathan Edwards

    The evidence for CBT in any condition, population or context... A meta-review... and panoramic meta-analysis, 2021, Fordham et al.

    Yes, it's a good thing that there are all these things to get annoyed about. Otherwise lockdown would get pretty dull.
  14. Jonathan Edwards

    The evidence for CBT in any condition, population or context... A meta-review... and panoramic meta-analysis, 2021, Fordham et al.

    A pity I had not been able to see this before answering questions at NICE committee - i.e. did I think CBT trials were just as rubbish in other conditions (shock horror). The fact that this review is unable to identify good quality evidence in anything and pick it out and has to bundle...
  15. Jonathan Edwards

    Trisha Greenhalgh on ME/CFS and Long Covid

    I agree. I think we should know what was said at this sort of level of medical propaganda.
  16. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    This looks to me confused. Do we know that these readmissions and deaths have anything to do with 'Long Covid'. There are a number of reasons why people bad enough to go into hospital with Covid might be readmitted last a high rate and die, including pre-existing poor health and organ damage...
  17. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    I think this might be an advert: One supplement the team had been developing specifically for “long Covid” patients had shown promising results, leading to faster recovery in some, Ng said. I am not sure what it would mean for 40% of Chinese to have 'dysbiosis'.
  18. Jonathan Edwards

    Oxalates may be a problem for people with M.E.

    Is there any reliable scientific basis to this @Sandra? Sure, if you have a tendency to renal stones it may be sensible to avoid high oxalate foods but that is not an issue of sensitivity. A lot of that site looks like pseudoscience to me - do you think it has a real basis?
  19. Jonathan Edwards

    Trisha Greenhalgh on ME/CFS and Long Covid

    I have a feeling that Greenhalgh has boxed herself into a corner in various respects. The strident advocacy for LC together with the deafeningly silent approach to ME, when there is no doubt that they overlap to a very large degree will soon enough appear ridiculous. Denying the existence of a...
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