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  1. Jonathan Edwards

    The 'C' in RCT

    Thinking about it I guess the key issue is the politics of journal editing. The two most prominent editors in the UK seem to have node about basic quality assurance.Maybe because they were both career journalists with a medical degree rather than respected physicians whomever later into...
  2. Jonathan Edwards

    The 'C' in RCT

    I think the problem is that all junior medics are taught to recognise obvious flaws in control profiles and in most of medicine they go on applying that knowledge, but there are islands within medicine where the obvious is just ignored. If PACE had landed on my desk as a member of the UCL ethics...
  3. Jonathan Edwards

    The 'C' in RCT

    You are absolutely right, Barry. AsI have probably said before, part of the problems a bad habit that philosophers are often guilty of, despite it being pointed out by the philosopher Wittgenstein - that they were taking language on holiday. The problem is the assumption that language works...
  4. Jonathan Edwards

    The use of the labels ME, CFS, ME/CFS

    I just think we need to have some idea what is going on.
  5. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    I think we can probably exclude that. P9-5 sounds like some sort of statistician or number cruncher who for some reason has a vested interest in healthcare finance. Maybe in a rather drudge job relieved by the excitement buying stocks in spare time. Possibly just bananas though.
  6. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    I am not aware of this ever being a sober look orbiting detached. It is just chucking out another buzzword. I think the situation is clear - there is no evidence of brain inflammation. And the clinical picture does not even suggest it. I am not sure there is so much doublethink here as...
  7. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    Simple, because GRADE allows assessors to downgrade at their own whim. The system is garbage. The whole idea of starting from the premise that randomised trials are brilliant and then you can downgrade them is completely bogus. You don't start anywhere and change. You assess the study. If it is...
  8. Jonathan Edwards

    ‘Give me back my fact: How can social science help us survive the post-truth pandemic?’, Campaign for Social Science SAGE Annual Lecture 2020

    And of course Greenhalgh's own effort to do some qualitative research on a few people with Covid-19 is laughable. It allows her to prove that Covid-19 probably isn't ME because the patients 'know' their fatigue is due to organ damage that presumably, if they have Long Covid, isn't there.
  9. Jonathan Edwards

    ‘Give me back my fact: How can social science help us survive the post-truth pandemic?’, Campaign for Social Science SAGE Annual Lecture 2020

    So why is Greenhalgh talking of deconstruction- which is to do with there being NO facts (Derrida) and belongs to what used to be a fringe touchy-feely branch of social science but seems to be takin over. And what has social science got to do with people spreading lies, I ask myself? Certainly...
  10. Jonathan Edwards

    ‘Give me back my fact: How can social science help us survive the post-truth pandemic?’, Campaign for Social Science SAGE Annual Lecture 2020

    I have tried to work out what it is that is supposed to be being said in the social science article. Rather like the Turner-Stokes and Wade piece it seems all completely arse-over-tit. Greenhalgh talks of post-truth (which Wikipedia says is where emotional arguments win out over facts) but...
  11. Jonathan Edwards

    ‘Give me back my fact: How can social science help us survive the post-truth pandemic?’, Campaign for Social Science SAGE Annual Lecture 2020

    To tackle the problem, she emphasised the need to draw on the ‘social science of science’ to produce a 21st-century post-truth account of what science is. What the Baloney does this mean? Maybe it should have been: She encouraged scientists and researchers not to shy away from their...
  12. Jonathan Edwards

    The use of the labels ME, CFS, ME/CFS

    Dear Guido @Guido den Broeder , My view as a physician is that this description is of a disease that does not actually exist. It brings together a number of historical speculations but in the last two decades as far as I know nobody has found any good evidence for the existence of such a...
  13. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    Yes, I thought that was rich - so I described their claims in my rapid response as coming from a 'small number of service providers'! Very much smaller. They contradict themselves right the way through.
  14. Jonathan Edwards

    Is ME an immunological disease?

    Still waiting I am afraid. Rather little has come out on this recently.
  15. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    As a German virologist points out in a Guardian quote, the extra spreadability of this variant is actually very hard to be sure of. I now realise that the massive increase in proportion of cases being this variant in SE England could just be a super spreader effect. If restrictions are...
  16. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Looks like pseudomedicine to me. Pretty much all of it is made up. There's no cytokine storm in Covid-19 and even if there was it would not be due to norepinephrine. Nul points I am afraid.
  17. Jonathan Edwards

    UK - NICE guideline on Long Covid

    Yes, but to be fair, what else could be said? People with motor neurone disease are high and dry too because there is nothing to be done.
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