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  1. Jonathan Edwards

    Coronavirus - worldwide spread and control

    In the UK the flattening preceded the half term holiday. I am not clear what these sudden flattenings mean because I don't think they fit a simple model. My best guess is that they relate to the superspreading issue, which can be switched off suddenly as a result of adjustment of behaviour in...
  2. Jonathan Edwards

    Coronavirus - worldwide spread and control

    NowI think may be more confused. The chances of my having a recurrence are very small!!
  3. Jonathan Edwards

    Coronavirus - worldwide spread and control

    That should have been chances, rather than changes - as may have been obvious.
  4. Jonathan Edwards

    Coronavirus - worldwide spread and control

    That sounds sensible, if for complicated reasons. Information from my daughter is that Covid infections have been pretty rife in schools, with a lot of schools brushing things under the carpet. I suspect much of the recent upsurge is due to schools and universities. But I strongly suspect that...
  5. Jonathan Edwards

    Coronavirus - worldwide spread and control

    Don't worry, @Sasha, I am not at all stressed by it. I have had the very best of care (organised by my wife's diligence in researching the problem) and am fortunate in that I know exactly what needs to be done when anyway. If I have a recurrence, as is usually the case there will be no rush...
  6. Jonathan Edwards

    BPS attempts at psychologizing Long Covid

    Stress is triggered in these cases (as in the case of whiplash injury, the Gulf War syndrome [2] and other symptom diagnoses) by the individual being exposed to a death threat but surviving. [...] Really? My wife and I have both been exposed to death threat but surviving more than once. I have...
  7. Jonathan Edwards

    Coronavirus - worldwide spread and control

    I think you may have been misled. Certainly in the UK hospitals were overfull before the pandemic. During it both patients and staff were getting infected with Covid and dying on a regular basis. I don't think health services have in any way over-reacted. I get a direct account from my niece...
  8. Jonathan Edwards

    Coronavirus - worldwide spread and control

    Yes, I am sure there will be deaths. The simple point is that if restrictions to air travel and social events had been put in place sooner none of these delays would have been necessary. Although if Canada is like the UK significant backlogs for surgeries had been around for twenty or more years...
  9. Jonathan Edwards

    Coronavirus - worldwide spread and control

    Yes, I may not have been very clear - they will not see her because they judge it too dangerous for all concerned. The A and E situation is different - that may have confused. Emergency care is not restricted but elective care has got pushed out because the system cannot cope. I was trying to...
  10. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    Interesting but difficult to know how to interpret. A prospective study with follow up would be more meaningful. San and co have been interested inertia-follicuar B cell activation for some time, as were we at UCL - looking at antibodies bearing the VH4-34 framework epitope recognised by the 9G4...
  11. Jonathan Edwards

    Coronavirus - worldwide spread and control

    I think there is a confusion here. The idea that restricting are causing deaths from other conditions is misinformation being spread by people who don't like the restrictions. The restrictions - pub closing, travel limits, rule of six, shops closing - have NOTHING WHATEVER to do with the...
  12. Jonathan Edwards

    NICE ME/CFS draft guideline - publication dates and delays 2020

    I think it is quite deliberately making use of the BPS doublespeak that says of course there is a biological trigger so the disease is not 'primarily' either B or P or S. It is all mixed in a way that all the answers are right. It might of course be coming from the subconscious via the id...
  13. Jonathan Edwards

    Coronavirus - worldwide spread and control

    As I see it Sweden obviously took the wrong path when other countries introduced restrictions and got their case and death rates well down. Sweden does not look quite so bad now because these other countries relaxed their restrictions too early and have caught up or even overtaken Sweden. I do...
  14. Jonathan Edwards

    NICE ME/CFS draft guideline - publication dates and delays 2020

    BACME supports grading activity strategies when delivered by an ME/CFS specialist clinician to make increases and improvements in physical, cognitive and emotional function from an identified stable baseline. It does not look to me like any real change in policy. They may have used a model...
  15. Jonathan Edwards

    Coronavirus - worldwide spread and control

    I agree. Moreover, for all those other diseases that we cannot quite eradicate, like TB and measles, the policy is to keep trying our best to eradicate. Only that way do you have a tolerable situation. In the UK the effort to control TB has got so stretched that in our area it is much more...
  16. Jonathan Edwards

    Substrate utilisation of cultured skeletal muscle cells in patients with CFS, Tomas et al, 2020

    Was just complaining that there are NO results in the abstract. If an abstract is this badly written I cannot be bothered to read more.
  17. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    Indeed. It sounds like some sort of junior medical subculture jargon that does not even appreciate what the term is designed for. I have never heard of it used in this sense. It does not even mean non-specific. It just means no more was said. So a crossbill is perfectly well described as a bird...
  18. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    I agree. The author sounds very naive as a medical professional. But maybe hates not unusual!
  19. Jonathan Edwards

    Substrate utilisation of cultured skeletal muscle cells in patients with CFS, Tomas et al, 2020

    "Results show that CFS skeletal muscle cells are unable to utilise glucose to the same extent as healthy control cells." It says in the abstract. But where are the results? What they show is for the reader to decide. This is not how science is written, sorry. If the findings were due to...
  20. Jonathan Edwards

    NICE ME/CFS draft guideline - publication dates and delays 2020

    Yes, but that sweeps everything under the carpet, as Robert points out. NICE is about what the NHS should provide, based on evidence. If we allow that a therapy is used on any old disease we have exactly the case Lynne Turner Stokes is making for rehabilitation exercises for Long Covid - it...
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