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  1. Jonathan Edwards

    Epilepsy and non-epileptic or dissociative seizures (FND?)

    Did anyone in the video implicate 'repressed emotions'? I certainly think that is bunk. But there needs to be a name for these non-epileptic seizures. FND would do for me if it did notary the baggage of BPS. If used by neurologist who admits we do not understand the mechanism I am not sure what...
  2. Jonathan Edwards

    Epilepsy and non-epileptic or dissociative seizures (FND?)

    I missed that. But I was encouraged that his final words were more or less 'I don't know'. I think it is reasonable to suggest that non-epileptic seizures originate from activity of those parts of the brain that are responsible for what we call 'mental' events. In fact epilepsy does too. I also...
  3. Jonathan Edwards

    Coronavirus - worldwide spread and control

    If you look at the cases per million on https://www.iancampbell.co.uk/covid-19.php and compare Sweden with similar countries (Norway, Finland) it is pretty bad and has the same uptick coming, despite there being no lockdown to be lifted. Most of the deaths in Europe have been due to infection of...
  4. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    I think that the problem is that a 'positive' antibody test is always defined by an arbitrary cut-off on a particular assay. There are always a few normal people who have levels a bit away from the massif the population.Nobody has a completely negative binding to an antigen.
  5. Jonathan Edwards

    Coronavirus - worldwide spread and control

    I keep wondering if we got it wrong about Sweden but then: The other three Scandinavian countries have death rates per million of 50, 62, 112 Sweden is 581, up with the worst cases like UK, USA and Latin America where at least there is the excuse of population density.
  6. Jonathan Edwards

    Epilepsy and non-epileptic or dissociative seizures (FND?)

    I did not listen to the whole thing but I was impressed at the end of the section on 'Andrew' when the neurologist admitted that he did not know the answer. I did not hear the term FND used but maybe that was earlier? I thought there was a contrast with Dr Barrett who seems to know the answer...
  7. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    Potentially interesting. It would be useful to have some control antigens studied. For instance heat shock protein 60, which pops up as a non-specific result in all sorts of situations where there is B cell activation. I am a bit puzzled by there being antibodies to all sorts of different...
  8. Jonathan Edwards

    BPS attempts at psychologizing Long Covid

    Indeed, the journalistic version of the same drivel we got from Wessely and Sharpe. In a way to see it written like this reveals just how pathetic the mind body story is. The whole 'psychology' story. Some reasonable science is done under that label, but so much else is the antithesis of science.
  9. Jonathan Edwards

    Chronic fatigue syndrome and fibromyalgia-like symptoms are an integral component of the phenome of schizophrenia, 2020, Maes et al

    Indeed. I feel rubbishy from time to time and would probably score a few points on ME and FM questionnaires. I have constant pain in more than four places for instance - but so what.
  10. Jonathan Edwards

    Chronic fatigue syndrome and fibromyalgia-like symptoms are an integral component of the phenome of schizophrenia, 2020, Maes et al

    As far as I can see they are saying that a good proportion people with schizophrenia feel rubbishy and particularly the ones with bad schizophrenia. Which is no surprise.
  11. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    I agree that this advice seems reasonably sensible. I do wish it wasn't written in such a (p-m-)aternalistic style as if the advisors knew what to do when nobody does. But at least the advice is mostly based on patient experience. It would have been even better if they just quoted patient...
  12. Jonathan Edwards

    Psychosomatic medicine and the psychologising of physical diseases

    I agree entirely. Either psychology is the study of mind in the sense of conscious thought, in which case it does not cover 'conversion' or it is the study of brain processes as a whole. As an empirical account of the latter it could be valid but in the absence of any understanding of mechanism...
  13. Jonathan Edwards

    Psychosomatic medicine and the psychologising of physical diseases

    There is no doubt that people have limps that disappear like that. But it is less clear exactly what is meant by psychosomatic and whether it applies. There is a beggar who asks for money on the North Circular Road at Enfield who limps grossly as he passes the cars with is cup shaking one way...
  14. Jonathan Edwards

    Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS, 2020, Lipkin et al

    I don't think I said that! I have no idea what a command and control B cell would mean.
  15. Jonathan Edwards

    Mast Cell Activation Syndrome (MCAS) - discussion thread

    I do not know much about mastocytosis other than that it is uncommon, is associated with an increased number of mast cells and is quite distinct from MCAS. I think it highly likely that symptoms in mastocytosis would be increased with exercise or cold or heat because these are stimuli that can...
  16. Jonathan Edwards

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    People with an hEDS diagnosis have more mobile joints - at least some of them. One of the reasons for joint mobility may be having longer ligaments relative to the distance between bony insertion points. This is certainly not the only possible reason, since bone geometry may also contribute (for...
  17. Jonathan Edwards

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    The government has taken a number of measures to mitigate the consequences of the pandemic. Among other things, the government decided in June on temporary exemptions which means that sick leave under certain conditions should not be tested against normal work after the rehabilitation chain day...
  18. Jonathan Edwards

    Psychosomatic medicine and the psychologising of physical diseases

    Yes, I get that too, but it is recognisably different from typical stammering. Maybe this just demonstrates that the original question is a bit hard to pin down.
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