Search results

Financial burden of patients with post-acute COVID-19 syndrome Jennifer Scheel-Barteit, Caroline Floto, Henrike Höpfner, Thomas Kühlein, Bettina Hohberger, Maria Sebastião [Line breaks added] Aim The present study aimed to analyze the financial burden of German patients with Post‐acute...

If by noise you mean confounders like people with ME/CFS might be more likely to take contraceptives, that's still totally possible, no disagreement here. That's not the kind of noise this kind of statistical test is testing for though. The p-value is small enough to say that the reason the...

More press about this paper: Blog by one of the authors: "A do-or-die moment for the scientific enterprise" Retraction Watch: "Fighting coordinated publication fraud is like ‘emptying an overflowing bathtub with a spoon,’ study coauthor says" Edit: Note from the blog:

One test is testing if either group's correlation is different from zero. The other is testing if the groups' correlations are different from each other. The first not being significant doesn't mean there's definitely no correlation between these metabolites, just that with the data we have...

Do you mean that it doesn't appear to be statistically valid? Each group on its own might have a correlation that is too small to be statistically significant when you're testing if the correlation is different from zero correlation. But the distance between the correlation in ME/CFS and the...

Is it possible that a contraceptive changing one hormone level might lead to downregulation or upregulation of these core enzymes so that many more hormones are affected than just progesterone?

The point isn't that meds would break down those channels. It's that if half the people take a med that increases the output metabolite of a pathway and half don't, with the input metabolite not being directly affected, the correlation between the input and output becomes much harder to detect...

I'm having trouble imagining how a specific factor would eliminate 52 (virtually all) different correlations between different metabolites. The simplest explanation to me seems like increased variability preventing significance. And I can imagine there might be increased variability in hormones...

ME Research UK e-newsletter – July 2025

Interesting that males are more at risk than females of clinically diagnosed PACS here.

Sociodemographic factors, biomarkers and comorbidities associated with post-acute COVID-19 sequelae in UK Biobank Marta Alcalde-Herraiz, Shahed Iqbal, Jeffrey J. Wallin, Yunhao Liu, Wildaliz Nieves, Mark Berry, Marti Catala, Daniel Prieto-Alhambra & Junqing Xie [Line breaks added] Abstract...

Association of COVID vaccinations and treatments with long COVID beyond 6 months: a case-control study on the adult population in a large integrated healthcare system in the United States from 2020 to 2023 Curtis Liu, Celina Liu, Rui Yan, Davida Becker, Jia Xiao Shi, Jeffrey Slezak, Diane Jerng...

Effect of nonpharmacologic therapies on depressive symptoms in patients with chronic fatigue syndrome: a network meta-analysis Baiyi Jiang, Mengru Cao, Xue Xia, Long Wang Background Depression or depressive symptoms exacerbate the burden in patients with chronic fatigue syndrome (CFS). The...

Neuroimmune Modulation in Adults with Rheumatoid Arthritis and Inadequate Response or Intolerance to Biological or Targeted Synthetic DMARDs: Results at 12 and 24 Weeks from a Randomized, Sham-Controlled, Double-Blind Pivotal Study John Tesser, Joshua June, Pendleton Wickersham, Jane Box...

Gulf War Illness and Inflammation: Association of symptom severity with C-reactive protein Lisa M. James, Brian E. Engdahl, Rachel A. Johnson, Apostolos P. Georgopoulos [Line breaks added] Abstract Gulf War Illness (GWI) is a chronic multi-system condition that has affected one-third of U.S...

Posts about Hilda Bastian's new blog post were moved here: Blog: Hilda Bastian "Six Months Later: What Their Response on ME/CFS Tells Us About the Cochrane Collaboration"

S4ME got a mention:

Science: "Genomewide study makes ‘quantum leap’ in understanding stuttering" 'In the new study, researchers turned to 23andMe, which assembled a vast database of users’ genetic information and other data. They analyzed the genetic profiles of 99,076 users who answered “yes” to the company’s...

Starting this thread because apparently at least several major celebrities had/have Lyme Disease (possibly Post-Treatment Lyme Disease Syndrome which is similar to other post-infectious conditions like long COVID). Most recently: ABC News: 'Justin Timberlake reveals Lyme disease diagnosis'...