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I was wondering why they wouldn't do this, and instead used some kind of simulated dataset, but then I thought maybe it's because the STRING database basically has all the "answers" for well-characterized diseases. So maybe if the model is looking at a well-studied disease, and sees high...

I think it was Janeway's Immunobiology I remember it from, though I don't have access to it now, that said type 1 response is mainly ILC1, Th1, and IgG for intracellular pathogens, type 2 is ILC2, Th2, and IgE for parasites/intestinal bacteria, and type 3 is ILC3, Th17, and maybe IgA for...

Thanks! This kind of activity is one of my favorite things to do. I wish I could spend hours per day learning about this kind of statistics related work, but I'm energy limited to around 10 minutes per day on average, with occasional overreaches like this when I get excited about an idea. Yes...

The preprint says all the genetic data is on Synapse.org (have to request access, not sure how easy that is), so maybe someone who knows how can test that. Edit: The note about the data was added in version 2 of the preprint.

I assumed it would include Th2 cells?

Why didn't they include the odds ratios for the last three medication risk factors?

Estimating Long COVID-19 prevalence across definitions and forms of sample selection Pietro Giorgio Lovaglio, Fabio Borgonovo, Alessandro Manzo Margiotta, Mohamed Mowafy, Marta Colaneri, Alessandra Bandera, Andrea Gori, Amedeo Ferdinando Capetti [Line breaks added] Abstract Long COVID (LC) is...

Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk Emilie T. Reas, Austin Alderson-Myers, Seraphina K. Solders, Qian Shen, Charlotte S. Rivera, Xin Wang, Jordan Stiver, Sarah J. Banks, Jennifer S. Graves...

I think in the US, anyone with private or government health insurance can get it for free. Both doctors I've had over the years have asked if I want a flu and COVID shot when the time of year comes around.

San Francisco Chronicle: '36 people with long COVID tested a potential treatment. Here’s what the study found'

This study? Exercise does not cause post-exertional malaise Gulf War Illness: A randomized, controlled, dose–response, crossover study, 2024, Boruch et al. I would hope that didn't cause a decrease in discussion. The thread was almost all criticism. They possibly showed that not everyone with...

Incidence of Long COVID diagnoses in 3.6 million US Medicare beneficiaries with COVID-19 Yasin Abul, Daniel A Harris, Preeti Chachlani, Kaleen N Hayes, Andrew R Zullo, Vincent Mor, Stefan Gravenstein [Line breaks added] Background Long COVID incidence and risk factors in older adults need to...

Long COVID and endometriosis: a systematic review and meta-analysis Alexandre Vallée, Maxence Arutkin, Pierre-François Ceccaldi, Anis Feki & Jean-Marc Ayoubi [Line breaks added] Abstract Long COVID conditions entail the persistence of COVID-19-related symptoms for at least eight weeks...

Genes mentioned in the abstract: AGXT MAB21L4 ATG4B AOPEP CEMIP SNCG

Unraveling the genetics of gulf war illness in diverse participants enrolled in the million veteran program Gita A Pathak, Dora Koller, Brenda Cabrera-Mendoza, Alice B S Nono Djotsa, Frank R Wendt, Antonella De Lillo, Eleni Friligkou, Jun He, Manuela R Kouakou, Linh M Duong, Jacqueline Vahey...

I think a few studies that found increased COVID proteins in LC. It's been a while since I read it, but I think this opinion paper covers the main ones...

Live blog of the symposium from the Sick Times: https://thesicktimes.org/2025/05/16/live-blog-following-the-spring-2025-polybio-symposium-on-long-covid-and-related-diseases/ Some snippets:

https://bsky.app/profile/betsyladyzhets.bsky.social/post/3lpcj2jai3k2k From Betsy Ladyshetz: "Real bombshell of an update from Michael Peluso in this symposium: UCSF's highly-anticipated monoclonal antibody trial did not find the treatment helped alleviate Long COVID symptoms. He speculated...

Comparing to the old version, I think this is the only difference: 2023 "Between 17 and 30 million people are estimated to have ME across the world, or approximately 1 in every 250 people." 2025 "50 million people are estimated to have ME across the world, or approximately 1 in every 165 people."

Moved posts https://bsky.app/profile/actionforme.bsky.social/post/3lpc5tl6qec2u Post from Action for ME: Link directly to factsheet PDF