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These systems are very interconnected, yes, and leptin and ghrelin can also affect insulin. :)

In this case the weight loss is not due to excess glucose, but due to the cause of excess glucose. Cells need insulin for glucose uptake, when they become insulin-resistant* glucose stays in the blood (and some will be secreted in urine). Since the cells are not getting glucose to turn into ATP...

Protein requirements are higher in many diseases, without it meaning anything else than the body having increased need in illness. I'd very much like to know if our illness is one of those where protein requirements are higher, for whatever reason. (I get tired of people overselling diet as...

My problem with this is that they don't discuss the possibility that the tendencies of improved secondary goals is related to the reduced step-count. I mean, they have thrown PEM into the mix so they should be aware of the possibility (although I don't feel their PEM question covers what PEM is...

And the trial registration clearly states participants would meet CFS criteria.

It does. And the conclusion that subsequent research should be done on patients with CFS comes out of the blue when they've focused so much on CF beforehand.

The use of CF and CFS in this text is indeed a muddle (also in the application). And the use of references is not in line with research integrity.

"That said, the increased recovery rate after 15 months in the intervention group might indicate that mental training for postinfectious CF is clinically useful." Still including the results from only the dropouts when talking about this, sigh. Both in the results and the discussion, which is...

Although I agree, the problem is not David Tuller and Jonathan Edwards, but someone not so eloquent or versed in science making the "wrong" criticism which is then used against us. I met a phd student at a course I was taking that had worked with Wyller and been told about a hate letter he...

And they changed parts of the aim of the study when they rewrote it. In the article with the qualitative interviews the study is listed as: "Malik S, Asprusten TT, Pedersen M, et al. Music therapy combined with cognitive behavior therapy for chronic fatigue following Epstein-Barr virus infection...

I'm not a native english speaker, but from the excerpt of her peer review I read it as she is clarifying what a feasability trial is to the authors, not saying this should be a feasability trial.

https://mmd.iammonline.com/index.php/musmed/article/view/679 My university is not a subscriber to the journal so haven't been able to read it.

Yes. And how does this square with that other study with results from the qualitative interviews? Which did say it was nested inside a randomized clinical trial.

Yes, that's right. Bonus points for international + high publishing rate.

Kennair at NTNU is the lead supervisor, while Wyller is a co-supervisor from UiO.

Can anyone get the new version, it seems they have republished it?

I'd like the second kind, although I must admit I would not volunteer to take part in such a study any time soon except on the researcher side.

Like I needed more things to complicate my B12 interest. A problem from the abstract is that "normal" levels of B12/cobalamin does not necessarily mean "adequate" levels of B12. Functional deficiency is diagnosed based on increased MMA levels when B12 is within the normal range. And "normal" is...

Article about the new diagnostic criteria for fibromyalgia Dagens Medisin had an article about the new diagnostic criteria for fibromyalgia, with comments from Egil Fors who have been involved in some ME/CFS research at NTNU...

I looked up the 1998 thesis, in chapter 3.7 he writes about "Complications and post-viral illness" (hastily translated by me): His sources: Collier, R (1974): The Plague of the Spanish Lady. The influenza Pandemic of 1918-1919. Macmillan. Det civile medisinalvesen (1922): Sundhetstilstanden of...