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I heard about this from an article which discusses the paper and the history of Activia. https://arstechnica.com/health/2024/10/popular-gut-probiotic-completely-craps-out-in-randomized-controlled-trial/ Given the prevelence of probiotic and gut microbiome studies I thought it may be of interest

Key Points Question What is the effect of 8 weeks of treatment with at least 4.69 × 109 colony-forming units/d of Bifidobacterium animalis subsp lactis HN019 on complete spontaneous bowel movements (CSBMs) in individuals with constipation? Findings This triple-blindrandomized clinical trial...

I know people who are on lithium for life and it’s my understanding we have no idea why it works for bipolar disorders and there are significant side effects and possibility for complications. Seems a very odd thing to be trying here and a lot of reaching by the paper.

I can feel and share the frustration and anger behind everyone’s comments. You’ve expressed things so well. I pulled out a few quotes which I think sum it up for me. Above all it’s not patients than need monitoring or educating by healthcare professionals but the reverse. Because right now...

Hiccups can definitely be exhilarating for the mouth and decrease sleepiness.

Yes! And ‘strenuous and stressful activity (for you)’ could be things that are that essential.

Fizzy water feels fizzy and you can’t sleep while drinking? Ahhh

A write up of this has been posted by ME Research UK https://www.meresearch.org.uk/trpm3-dysfunction-in-me-cfs-and-the-potential-role-of-low-dose-naltrexone-ldn/

Sorry of this is trite but it feels like the most useful training for now would simply be: - Most of what you may have been taught or heard about ME is wrong - Patients severity and symptoms will vary, trust them and what they tell you It’s disheartening to hear how this process has been going...

I didn’t really notice a difference in my hand grip strength but when it was measured it was way down and dropped on subsequent tests. Hand grip strength as a clinical biomarker for ME/CFS, 2018, Nacul et al They appear to have just taken an average in this rather than look for any trends...

Maybe a temporary problem? The link is on their Facebook page and there are comments about issues accessing it but I just checked and it seems fine.

Threadreader version for those not on twitter https://threadreaderapp.com/thread/1841060345017721278.html

There seems to be a v2 of the paper posted a couple of days ago https://www.medrxiv.org/content/10.1101/2024.08.26.24312606v2

Thanks @SNT Gatchaman I’m fascinated by the changes our bodies undergo in space and the Twins studies have been really interesting. It would be ironic if some of the changes seen which previously put down to deconditioning were something else wouldn’t it? While we’re looking for life out there...

It’s amazing isn’t it! Did you hear the stories about the microbes on the space station and how they are evolving? I realised a while back that I mistakenly thought of medical doctors as scientists as they have usually done science things. For the most part they are not, they are more like a...

Interesting, I can’t read the whole article but I wonder if they are already or how long it will be until we do get into the good v bad bacteria side of things? Microbiomes appear to be very in vogue.

Link to watch and download the video. https://bit.ly/4didHTK I’ve not listened yet but from a skip through it has detailed presentations from various people on the different studies that have been taking place and their findings, looks very interesting.

That’s a good explanation of something that I recently realised seems prevalent and involved in many of the problems we see. Saying ‘I don’t know’ can be hard for all of us. Even more so for people who want to help and/or feel very highly of their own ability and/or feel a pressure to...

Good to see (As many will, I have family with Parkinson’s). As an aside It’s interesting to see direct quotes there from Parkinson’s UK’s information for journalists page, which I was looking at recently and wondering if ME charities could do a better job of communicating and advocating with...

It all sounds very press release-y if you see what I mean? Hopefully there’s something meaningful underneath it all. This page was shared in another thread I think, which has a link to a flyer with a bit more info: https://precisionlife.com/beginning-to-unravel-the-biological-drivers-of-me...