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I don't see how reducing circulation through capillaries would stop pathogens embolising (which is a pretty unusual situation anyway). I would have thought it would be better to open up the capillaries to encourage bacteria to be washed right through and on into the spleen. I am not sure that...

If the sports medicine people sense that business may dry up because of PWME refusing GET then they need to make sure it doesn't happen for Covid.

The soft whirring noise of vultures circling.

The bit about people with RA only limiting activity when it is intolerable is also garbage. When assessing an RA patient I would get a huge amount of information simply from the way they moved. Someone with RA walks differently, sits down differently, turns their head differently, and when you...

Seems like drivel. In 1985 occupational therapists were busy teaching RA patients 'joint protection techniques' to reduce the harm done to joints by usage. Most adults with RA keep going as much as they can because they find that unless they move their joints as much as possible during the day...

Have they? I don't think I ever have. If I am fatigued and try to do something I usually just feel even more fatigued. I may be pleased to have done something essential, like fasten down a dinghy in a force 8 gale in the middle of the night, but I don't recognise the idea of 'overcoming fatigue'...

Very much agree. To me the key error here is muddling an explanation of what happens normally with an explanation of what happens in disease. It is similar to the story of 'molecular mimicry'. The story for molecular mimicry is: the immune system has a sophisticated mechanism for leaving self...

I don't think anyone is likely to want Garner as a spokesperson.He is completely off message for all the relevant vested interest groups except perhaps Phil Parker. BPS people are not going to want people to think you can close down all the liaison psychiatry and rehab centres and employ...

I think the press just like a professor who talks touchyfeely bullshit. He is wonderful material - splurging nonsense about stress.

Am I right in thinking that all the other pseudoprofessors have gone bit quiet except Garner? Has he not noticed that the Fat Lady has already sung on this story? Will Cochrane be organising a discreet neutralization?

Oh but now it is all individualized and nothing to with GET. Need to keep up with the trend!

Haven't you ever tried to straighten out a bedspread, @dave30th ? First you have to pull it one way and then you have to pull it the other way and then you have to go back and pull it a bit more the first way and ....

From my perspective a consensus is just when at a scientific meeting if you went round asking people if such and such a finding looked solid most would say yes. It has nothing to do with any specific number of studies. It has much more to do with convincing detail in a very few studies. If...

I am not sure that there are any data on a decent population based cohort. Reports from people like Peter Rowe are hard to make anything of because they involve tertiary centre referral cohorts that are probably heavily influenced by presuppositions.

I wonder what exercise therapy is doing in 'psych advances'? Presumably there aren't too many actual psych advances.

By consistent physiological abnormality I really just mean finding the same thing each time people look. So one study finding low NK numbers and normal function and another showing normal numbers and low function is no good. It is also no good if the findings don't look to be measuring the same...

I think the ethics committee put it well and Gunderson missed the point. There is often likely to be allegiance or competing interest but then you have to make your methodology immune to that. Although the ethics committee seem to have missed several tricks I thin they got this one right. Fluge...

I don't see a problem with the threshold. When the research community finds something solid consensus on that falls into place pretty automatically. Nothing in the ME field except perhaps the CPET stuff gets near the level needed. @Snow Leopard is the person who understands the CPET issues...

Sadly I don't think anything has changed. The NK story looks dead now. The CPET story may start to hold up with further studies reported but I for one still find it quite hard to see clear evidence of a consistent physiological abnormality.

EUORMENE is an organisation set up by researchers - specifically by Derek Phoebe the UK epidemiologist. It is a collaboration between European ME researchers and got a COST Action grant about four years ago to study research needs and education. Various publications have resulted. EMERG was...