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  1. ME/CFS Science Blog

    Trial Report Randomized controlled trial of intravenous immunoglobulin for autoimmune postural orthostatic tachycardia syndrome (iSTAND)

    Yes strange that IVIG had the lowest decrease in mean score but the highest percentage of improvers. The following figure is from their pre-print.
  2. ME/CFS Science Blog

    A body–brain circuit that regulates body inflammatory responses 2024 Jin et al

    Sounds interesting. Let's hope it is relevant to ME/CFS and post-infectious illnesses.
  3. ME/CFS Science Blog

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    "to answer the question, consistently completing the tasks is not a requirement for a valid effort test administration" But the problem is that the task likely required more effort for patients than controls. Lower completion rate is probably only a reflection of that, as was the proportion of...
  4. ME/CFS Science Blog

    Neurostimulation

    There have been several local news articles where chronic pain patients report improvement with a neurostimulation device that unfortunately costs tens of thousands of euros. Some ME/CFS patients with chronic pain have asked about this too. Does anyone have experience with it or is anyone...
  5. ME/CFS Science Blog

    Trial Report Validity and diagnostic overlap of functional somatic syndrome diagnoses, 2024, Rosmalen

    They found a prevalence of 3.1% for CFS (Fukuda-criteria) which is abnormally high. I think this could be the reason: "the FSS diagnosis was based on the responses to a questionnaire, without an assessment by a physician. The large sample size required for the current study implied that it was...
  6. ME/CFS Science Blog

    Development of an expert system for the classification of myalgic encephalomyelitis/chronic fatigue syndrome 2024 Yagin et al

    They needed 50 out of 832 available metabolites for a model to separate patients and controls. To me that suggest they had a really hard time separating the two groups.
  7. ME/CFS Science Blog

    The Netherlands - €28.5 million ME/CFS research program - ZonMW funding awards announced April 2023

    The webinar itself is available here: https://www.zonmw.nl/nl/nieuws/terugblik-webinar-over-onderzoek-naar-mecvs
  8. ME/CFS Science Blog

    The Netherlands - €28.5 million ME/CFS research program - ZonMW funding awards announced April 2023

    During the Webinar Rosmalen also answered to the question how Lifelines determines if someone has ME/CFS or not. This is a quickly translated transcript: Presenter: How are people in Lifelines determined to actually have ME/CFS? Rosmalen: As Sonja said, we start with a questionnaire and we...
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