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  1. Arnie Pye

    A proprietary herbal drug Young Yum Pill ameliorates chronic fatigue syndrome in mice, 2021, Yin et al

    The 2nd link triggers my internet security and says the page is dangerous.
  2. Arnie Pye

    British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

    There are an awful lot of references to "recommendation: strong, quality of evidence: low" in that paper, as well as quite a few references to "recommendation: strong, quality of evidence: weak". I am sure there is some logic to describing recommendations as strong while describing the quality...
  3. Arnie Pye

    The disabled doctors not believed by their colleagues

    I suspect one factor in this situation is that the people most likely to apply to study medicine must believe beforehand that they are healthy enough to do the training, which is well known to be physically and mentally demanding. Any medical students not up to the job will drop out or be kicked...
  4. Arnie Pye

    Long Haulers—What Is the Evidence for Post-COVID Fatigue?, 2021, Stengl et al

    @DokaGirl Excellent post - but depressing in view of all the time-worn stereotypes being trundled out yet again.
  5. Arnie Pye

    "Instead of believing my reports of pain, experts told me to have a baby or see a psychiatrist"

    From @Sean 's link in post #12 : Women have been believed to be fragile for ever. And yet there are parts of the world (Eastern Europe and the UK, for a start) where hysteroscopies are performed without anaesthaesia despite about 24% - 40% of women describing them as the most painful...
  6. Arnie Pye

    Article : The Absurdity of Peer Review

    I came across this tweet - which is a public tweet, and the thread it comes from is public too - no Twitter account required to read it : which was referring to this article : https://elemental.medium.com/the-absurdity-of-peer-review-1d58e5d9e661
  7. Arnie Pye

    Media items about obesity

    No surprises here... Title : Short-Term Energy Restriction Leads to Overall Increase in Appetite Link : https://www.endocrinologyadvisor.com/home/conference-highlights/aace-2021/reduced-caloric-intake-increased-exercise-increases-appetite/
  8. Arnie Pye

    Iron deficiency and dysregulation

    People might like this video, which just came out today, on "Blood Tests For Iron Status". The speaker is not the most compelling speaker I've ever heard, but his information was interesting. He discusses iron studies and ferritin in a general way, then starts to discuss results you might see...
  9. Arnie Pye

    Iron deficiency and dysregulation

    Could suspected low-grade inflammation in ME cause iron deficiency? I think inflammation could cause low iron in anyone, with or without ME - but I'm making a distinction between serum iron and ferritin (iron stores). Ferritin is an "Acute Phase Protein". This means it rises in the presence of...
  10. Arnie Pye

    "Instead of believing my reports of pain, experts told me to have a baby or see a psychiatrist"

    I've always thought that using babies as a commodity to reduce the load on the NHS was immoral. And knowing how my life went, in terms of health, if I'd had a baby in my late 20s, 30s or 40s I would have been completely incapable of looking after it. I did five rounds of IVF, got pregnant three...
  11. Arnie Pye

    "Instead of believing my reports of pain, experts told me to have a baby or see a psychiatrist"

    One day, many years ago, I had an appointment with a gynaecologist. It was February, I think, - not long after Christmas. I had had a Christmas present from my husband of a new briefcase, and I also had bought myself a new winter coat. I worked in an office and I was looking much smarter than...
  12. Arnie Pye

    Does pain neuroscience education appear to work because it teaches patients to downplay their pain?

    Can I stab someone in the abdomen with one skewer, and then stab them in the left kidney with another one? Both skewers need to be quite thick and driven in about 10 inches and wiggled about every minute or two? Then ask the person I've stabbed if they can just ignore the pain for the next 50...
  13. Arnie Pye

    How effective are common medications: ... meta-analyses of major drugs, 2015, Leucht et al

    Many people with indigestion, heartburn, and acid reflux actually have too little stomach acid, not too much. Rather than suppressing acid even more as PPIs do many people who try it find benefit in adding acid to their stomach when they eat. The valves at top and bottom of the stomach are...
  14. Arnie Pye

    UK: NHS data sharing – deadline imminent

    @Sarah Your link is behind a paywall, and there don't appear to be any options to read without some form of paying subscription. I looked at the websites of the organisations you list and found this reference to the legal challenge from openDemocracy...
  15. Arnie Pye

    Physical activity intensity but not sedentary activity is reduced in CFS and is associated with autonomic regulation, 2011, Newton et al

    If the weight distribution of the sick and the well were significantly different then the results of the study would be even less reliable than they currently are. I'm not knowledgeable on research methodology but I'm fairly sure that sick and well groups are supposed to be well-matched. So...
  16. Arnie Pye

    Functional gastrointestinal and somatoform symptoms five months after SARS-CoV-2 infection: A controlled cohort study (2021) Noviello et al

    I was feeling masochistic so I started reading the full text. Like so many of these kinds of papers it declares that the disorders being studied are functional and somatoform without explaining how they arrived at this conclusion. Testing appears to have been solely by questionnaire. Just to...
  17. Arnie Pye

    UK: NHS data sharing – deadline imminent

    Absolutely 100% agree. I wouldn't trust the government (no matter who was in power, now or in the future) with my medical records. I think they'd sell it the instant they got their hands on it. Even if the data was anonymised I still wouldn't trust them. I remember the joke method of anonymising...
  18. Arnie Pye

    “It’s not all nice and fun”: Narrating contested illness on YouTube and Instagram, 2021, Groenevelt

    I may be going off at a tangent slightly... Some societies and cultures don't recognise the concept of depression at all, and certainly don't have a word for the problem. Not a very good link, sorry : Title : A Look at Depression Around the World Subtitle : How depression is viewed in...
  19. Arnie Pye

    Dietary and herbal supplements for fatigue: A quality assessment of online consumer health information, 2021, Ng et al

    I have never come across a doctor who knew anything about DHSs. DHSs are defined as “products containing naturally occurring substances intended to supplement the diet, and restore or maintain good health,” encompassing vitamins and minerals, herbal remedies, homeopathic medicines, traditional...
  20. Arnie Pye

    Blog: "The patient voice: a biased or valuable source of information?"

    Let's hope the person who said this never goes into politics. It sounds like the kind of thought that might go through the head of a wannabee dictator.
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