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They used this method described in the paper: I didn't know what it meant, so I asked ChatGPT to write the Python to calculate this effect size, and using the provided code below I get 0.742. import pandas as pd import numpy as np from scipy.stats import rankdata # Sample DataFrame with paired...

Oh that is weird. I tried as well using age and height. In dataset 1, there are two participants with age 68 (heights 165 and 167.2), while in dataset 2, there is only one participant with age 68, and they have height 165. There's a participant listed with height 167.2 but their age is 54.

You could probably join on multiple columns (e.g. where all of sex, age and BMI match.

Investigating liminality in the lived experiences of young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Toller, L University of Exeter PhD in Sociology [Line breaks added] Abstract This study investigates the lived experiences of young adults (aged 18-25) with...

I think the main potential multiple testing issue would be where they looked at the association of CMV with 8 different domains of the SF-36, then only used the most significant for the followup linear regression. If there was barely any pattern of p-values, I'd be more concerned. But 5 out of 8...

The relationship of cytomegalovirus with physical functioning and health-related quality of life in older adults Frances A. Kirkham, Phu Sabei Shwe, Ekow Mensah & Chakravarthi Rajkumar Aims/introduction Cytomegalovirus (CMV) is a highly prevalent virus, known to be associated with...

Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients Toka Elboraay, Mahmoud A. Ebada, Maged Elsayed, Heba Ahmed Aboeldahab, Hazem Mohamed Salamah, Omar Rageh, Mohamed Elmallahy, Hadeer Elsaeed AboElfarh, Lena Said Mansour...

I haven't watched the video, but your summary sounds a lot like the things discussed in a previous video that I summarized in an earlier post. Bolded the parts that relate to a couple of your questions:

I looked at one claim in the response, high urinary creatine as objective evidence of muscle damage in ME/CFS. https://www.s4me.info/threads/urinary-creatine.44616/#post-616907 She cites one unpublished datapoint. Chris Armstrong's team published a paper that seems to show the opposite, but...

Latest preprint 14 June 2025 Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVID Zhongshan Cheng [Line breaks added] Abstract Long COVID presents a significant public health challenge, characterized by over 200 reported...

I just wanted to look at at further evidence for one claim supporting biochemical pathology from the response from Margaret Williams to Jonathan Edwards' hypothesis paper: This paper tested creatine in urine before and after exercise (along with 1400 other metabolites): Urine Metabolomics...

I don't think it's necessary to focus on. She apparently thinks Jonathan is blatantly wrong about that point, so it's understandable to sound a bit more defensive. I'm sure the writers of the "Patients with severe ME/CFS need hope..." paper consider some of the rapid responses they got...

@Jonathan Edwards, I'm not sure if you saw this response from Margaret Williams. She posted it on her website (PDF), and someone also shared it on Phoenix Rising...

The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome Don L. Goldenberg Introduction Long COVID is a condition characterized by persistent unexplained symptoms following COVID-19 infection. These symptoms are not related to...

That's interesting. Is this correspondence on the forum somewhere?

After looking at the paper again, I realized I should have done my GSEA analysis using p-values, not attention scores. I don't fully understand their method for interpreting the model, but p-values are the metric they used for choosing the top 115 that they say are the most important. It didn't...

I'm interested in the "intervention strategies" they would like to see. Specifically wondering if they mean treatment for mental illness.

Postacute Sequelae of COVID-19 Across 12 Major Health Domains and 141 Diseases in Individuals With Mental Illness Among COVID-19 Survivors: A Population-Based Cohort Study in South Korea Jiseung Kang, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Hayeon...

Executive Function Decline and Its Association With TNF-α in the Later Stages of Post-Acute Sequelae of COVID Aditi Varenya, K. Vijayalakshmi, Mythri Rajeswara Babu [Line breaks added] Abstract Beyond the immediate impact of the COVID-19 pandemic, survivors often grapple with incapacitating...