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Live blog of the symposium from the Sick Times: https://thesicktimes.org/2025/05/16/live-blog-following-the-spring-2025-polybio-symposium-on-long-covid-and-related-diseases/ Some snippets:

https://bsky.app/profile/betsyladyzhets.bsky.social/post/3lpcj2jai3k2k From Betsy Ladyshetz: "Real bombshell of an update from Michael Peluso in this symposium: UCSF's highly-anticipated monoclonal antibody trial did not find the treatment helped alleviate Long COVID symptoms. He speculated...

Comparing to the old version, I think this is the only difference: 2023 "Between 17 and 30 million people are estimated to have ME across the world, or approximately 1 in every 250 people." 2025 "50 million people are estimated to have ME across the world, or approximately 1 in every 165 people."

Moved posts https://bsky.app/profile/actionforme.bsky.social/post/3lpc5tl6qec2u Post from Action for ME: Link directly to factsheet PDF

Very interesting, thanks. Sounds like it could make for a good movie.

Well now I'm curious. Why are there people who care whether it's T cells or B cells? Just because that's the ones they've been working on thus far?

Cool, I appreciate the insights!

Interesting, thanks! I'll take your word for it if you say the neuron related scores aren't particularly interesting. But when I look at the number of neuron components, it seems like a lot near the top? I see that six of the top ten components are related to neurons (at least based on the...

I now see that this Zhang model is more telling us about clusters of genes with related function as opposed to the specific genes picked out. And I've been learning about GSEA the past few days. So I wondered, if I did a GSEA on the rare variants for chronic fatigue syndrome in the Genebass...

Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk Kaleem Maqsood, Shaaf Ahmad, Azeem Saeed, Nabila Roohi [Line breaks added] Highlights • Plasma fibrinogen and haptoglobin identified as biomarkers for long COVID severity. • Elevated...

Interesting since there's already an ongoing trial of maraviroc for long COVID: (Thread) Protocol - Investigating the Feasibility of Repurposing HIV Antivirals in Adults With Long Covid [tenofovir/emtricitabine or maraviroc]

A Multi-Center Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID/Post-Acute Sequalae of Covid (PASC) Brief Summary The IMPACT Long Covid Treatment clinical study (IMPACT-LC) is testing two...

Thanks for giving some reassurance at least.