Search results

Fibromyalgia and hand diseases: A case-control study Eli Magen, Suhail Aamar, Viktor Feldman, Israel Magen, Eugene Merzona, Ariel Israel [Line breaks added[ Highlights • FM triples risk of carpal tunnel, De Quervain’s, and trigger finger. • FM linked to higher rates of carpal tunnel release...

Endometriosis and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis Sabrina Compton, Rodolf Alkabalan, Judd Cadet, Azin Mastali, Prakash V. A. K. Ramdass Background/Objectives Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and endometriosis...

Unpublished trial of CoQ10 in GWI where it doesn't appear to help:

Now published: Gulf War Illness, Fibromyalgia, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID Overlap in Common Symptoms and Underlying Biological Mechanisms: Implications for Future Therapeutic Strategies David Mantle, Joan Carles Domingo, Beatrice Alexandra Golomb, Jesús...

Now published, see post #6 ------------------------------------ Relationships Between Fatigue, Cognitive Function, and Upright Activity in a Randomized Trial of Oxaloacetate for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Suzanne D Vernon, Candace Rond, Yifei Sun, Shad Roundy, Jennifer...

Anti-neuronal and anti-mitochondrial autoantibodies are associated with lower functional status and more severe respiratory symptoms in post COVID syndrome Antje Vogelgesang, Anke Steinmetz, Angela Stufano, Valentina Schino, Domenico Plantone, Agnes Flöel, Guglielmo Lucchese [Line breaks...

Cases are the ones with fibromyalgia. Controls are healthy. And I meant participants as everyone combined.

Maybe you meant total participants, but in terms of cases it's around 54,000. Around 3 times more.

I pulled up the top hits from this study and compared to DecodeME to look for those that are in the same general location as at least a somewhat significant locus in ME/CFS. So these images are the results for ME/CFS, but with the top fibromyalgia SNPs marked as black triangles and with their...

I see some familiar genes from DecodeME: RABGAP1L, OLFM4, DCC

I don't know if it's circular. It's more like NK cells might be relevant because of the study correlation. And ADCC might be relevant if NK cells are relevant. True, there might be other possibilities for why NK cells were significant (including randomness).

If we suppose that high NK count is related to better antibody dependent cell cytotoxicity, might the fact that the correlation was with blood NK cells provide a clue about where the cells that need to be killed are? The multiple myeloma studies found correlations with NK cells in the bone...

Well nothing indicated that people with high NK cells had worse ME/CFS. There's the possibility that NK count doesn't have much to do with the illness itself, it's just if you happen to be a person with high numbers, dara can work more effectively. An imaginary related example is if there was...

I think generally LD is related to where DNA tends to be cut when DNA shuffling is happening during cell division. I'm not sure if there's any relation between regions that tend to stay together and the locations of specific genes, but maybe it happens. I don't know enough to say it's not...

Hmm, I'd be cautious about ascribing similarities in length between a gene and a signal as more than a coincidence. Here's that area except with LD colors in reference to the top SNP (purple diamond) of that little length of SNPs: It looks like that's just a stretch of SNPs that are in strong...

Discussion about the interpretation of high p values was moved to this thread: Understanding Statistics

I brought this up with the author of the blog post. He stood by his statements and I would tend to agree with him. I didn't ask for permission to quote his response, so I won't copy it. Part of his response though is that he thinks the statement from the ASA might be being misinterpreted or...

Now published: Burden of Disease in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Scoping Review [Line breaks added] Objective Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious chronic and complex multi-system disease characterised by symptoms such as...

Thanks, updated title. I assumed it was going to be DaraME to follow the theme of CycloME and RituxME.

Any chance you measured NK cell count around that time? Or ever?