The first time I was on metformin (for diabetes) I kept going hypoglycemic, so I stopped taking it. The second time I had a leg go black and four...
On a related note, maybe 25 years ago I proposed on a science forum that mitochondrial oxidative stress, and in particular a lack of glutathione,...
With the caveat that discussions on this thread are speculation, though often backed by personal experiences, I have some ideas. First, about...
Going out on a limb, way before there is sufficient evidence or I fully understand the claim, I could argue the Perikles hypothesis is basically...
https://www.healthrising.org/blog/2024/06/21/anaerobic-exercise-long-covid-chronic-fatigue-oxygen/ There are further links inside the article,...
Just clarifying my thoughts on baselines. If an activity program uses a baseline its probably not an adaptive process, but a graded one. If...
My biggest problem is not forcing myself to do more, its holding myself back from doing too much. Especially when there is need of more activity...
Decades of experiences teaches me that baselines are nonsense. One year its mostly about one level, another year it can be higher, then much...
I think not just the brain but some ganglions.
In discussing mTOR activation, I would like to see how this compares to mTOR activation in type 2 diabetes. If the model is to even try to explain...
I have donated in the past, but do not any more. I need every cent. However my will donates everything to ME research. I keep vacillating on...
Tying -omics to severity is a recent hope of mine. I have not read the paper yet so cannot be sure it does so properly, but the goal seems worthy.
While I suspect many mechanisms are going on, eating a meal diverts blood to the gut. If we have insufficient blood to the brain, like in POTS,...
My response to CoQ10 is over a wide range. I have had boosts to energy levels, allowing me to finish my university studies. I have had zero...
Less commonly now, almost rare, but I used to have them all the time and some I know with ME and sore throat have sinus issues almost constantly....
Hi, anecdotally I have had discussions on this many times with other patients. I have a constant dry sore throat. So do many of us, but it can...
Our bodies can make most saturated fats, but not all. What we can do is convert some fats that are similar to the essential ones, but I have not...
There are so many potential confounds here. Even presuming they are correct in their findings, and I do not, they probably have an association,...
Nick Norwitz recently cowrote a paper on lean mass hyper-responders, using their new lipid energy model. Cholesterol goes way up but there is no...
Moved post In about 2015 I had multiple incidents of me misremembering, or just not remembering at all, plus the usual focus issues. I stopped...
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