I wonder more about the neuropathy being associated with fatigue in Fabry disease. It is associated with SFN including autonomic dysfunction and...
It's hypothetically possible, they both have metabolic effects (in terms of regulating blood sugar etc). But how do you know the insomnia is due...
I spent years, looking at all sorts of possibilities. The problem is that it is too non-specific, numerous metabolic disruptions can increase...
There is no "clear signal" of fatigue markers in the blood of anyone because the blood is not the right place to go looking. Anyway, back to the...
The immune system deliberately preserves antigen fragments for years, that is how we maintain serological (antibody) responses. If there is viral...
So they're assuming nothing will change in the evidence base between now and 2028
Makes me wonder whether metablind was cooked up to justify that aspect of GRADE... (yes I know it's a conspiracy theory)
It might be true for a small number of ME/CFS cases, but it is not true for the persistence of LongCOVID.
We can't find anything that we refuse to look for. No one has bothered to investigate the afferent nerves in ME/CFS with the exception of skin...
How are they measuring central sensitization? (rhetorical question, I know they aren't measuring anything, they're just using vague jargon).
I've had enough of these people's vague speculation. Show us some actual science please or GTFO.
Cause or effect? What they are writing is quite misleading. There is no generalised interoceptive impairment sense and any differences in...
People can hate me for saying this or whatever, but Cleare's 2003 review was actually quite decent for the time and there hasn't been much...
The key point is that cortisol is a feed-forward metabolic hormone. Salivary cortisol in particular adjusts to your daily sleep-wake cycle and...
Note that this is a research proposal based on a fairly simplistic narrative review.
Is it? They're just looking at the phenotype of T-cells in circulation and as I linked above, (a) T-cells in circulation aren't the ones that are...
I don't see the point of the comparison, sloppy science and bad experts should be questioned no matter who or what the focus is.
Some more information on the lifespan of T-cells (and note that a majority of T-cells are tissue-resident, rather than in blood.) "Memories that...
We knew that in January 2020. :whistle: Put alternatively however, it can also be said that the symptoms of these patients are also not due to...
And they had a huge difference in reported scores on the Bell Activity Scale.
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