Hi, I am curious as to whether anyone has some developed hypotheses as to the mechanism of 'low-dose' Naltrexone? Much of the discourse about...
Yes, very much this. The focus of TREATMENT (and treatment studies) is should not be about focusing on lowering or stopping the perception of...
Yes, but I'm finding it has gotten worse as I have gotten older. I used to be able to push through to do something, even if minimal, now not so...
Central fatigue is stimulated by peripheral afferents and the purpose of which is to lower peripheral fatigue! The two are 100% linked together in...
I get circulation issues like subconjunctival hemorrhage if I drink more than a bit.
The most frustrating part is when scientists and medical doctors invoke predictive coding to explain sensations where there is no evidence for...
The key point is the error signal in your example is generated the spine, it is not supraspinal.
The problem is that Cort doesn't understand what perception of effort is (in a neuroscience sense) and why fatigue leads to an increased sense of...
Einstein's early work was all based on reinterpretations of the empirical work of others. He was inspired by Hilbert's approach (in mathematics)...
Cue all the hype and old misinformation about "mucosal immunity" in the media. (hint the intramuscular COVID immunisations also led to antibodies...
I note the wording doesn't include ME/CFS. I wonder if they go with the neglected for years angle or the 'this is new' angle...
Crivens! Whut aboot us, ye daftie!
Why do you want to write about Effort Preference? The main mistake the authors make is looking at any differences and assuming they are...
Scale responses are not symptoms. More researchers who don't understand the danger of equating the two, failing to understand that modifying...
Todd Davenport regularly Tweets against the idea that exercise is helpful for ME/CFS.Perhaps what was written isn't clear enough, he is...
Dave Clark's article is not bad, but the whole thing reeks of a need to put a positive spin on disability.
I think it can, but it is a matter of severity, people with cancer might not want to hear it but cancer fatigue is usually on the mild end when...
I'm glad there is a shorter version. Is there a version of https://raffbenato.github.io/funcap55/ for the FUNCAP27?
The problem (for some) is indeed excessive vasodilation and I've seen more than a few people who swear by Midodrine for significantly improving...
Using mRNA vaccines for Flu is a step backwards in my opinion. Hopefully the clinical trials of the "universal" stalk-region influenza vaccine are...
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