That is encouraging but B cell survival in vitro is so temperamental that it would be easy to get an artifactual difference. You would really want...
I think that study could be very useful. So far we have one or two isolated cases of dorsal root ganglion changes that might have been by chance...
It might be quite hard to detect. If the inflammation consisted only of diffuse lymphocyte infiltration without oedema MRI might not show much. If...
Note that to get MS you pretty much have to have certain genetic variant risk factors. That might mean that AWOL B cells can only colonise brain...
I think this is the Post-Covid PASC study but still interesting. We have no evidence of focal demyelination lesions like MS in ME/CFS or PASC so...
Interestingly, there is another possible explanation - that a B cell committed to making antibodies to EBV cannot support its own EBV infection...
Or maybe stop more going in. Rituximab probably does that and if you gave it often enough to keep B cells out of the blood you might prevent any...
This is a big problem. Charles put a huge amount of effort into making the new NICE Guideline a reality. Now it seems that the MEA is happy to...
Would that be the water around the Norwegians when they jump in a freezing lake after a sauna - or is that the Finns? I have always thought you...
I have never seen anything immunologically credible about Ampligen. It has always looked like something based on garbled pseudoscience. I never...
One thing that may be relevant is the suggestion that Hemsley was thinking in terms of a private contracted service for feeding support outside...
So it is not just me confused it seems. It looks as if this recent document is it. But then Hemsley's reply is also pretty vague and makes no...
I can't see that.
Pretty much although it may be a bit more complicated.
This finding is very interesting and very consistent with the way I have always looked at MS - not as a cross-reactive disease but as a failure of...
My sense is that the only way to get it across is to point out in the same document that people like Maeve die if it isn't sorted.
I am not very well placed to start a thread just at the moment, with other things in the in-tray. What I think needs a decision is the scope of...
I agree. I have obviously put some thoughts into Qeios articles with a different purpose and format but I think it would be a nice idea to try to...
A pity that University press releases mangle the science so much. What on earth are 'genomic hitch-hikers'? They seem to have missed that there...
Yes, I get the impression, although he says things in a roundabout way, that he wants a causal concept and maybe would prefer ME. One thing that...
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