Correct, apparently they also play a part on innate immune system, Gut dysbiosis, glucose control and other important functions. An example for...
Thank you for the mention @ScottTriGuy ! The hypothesis is a bit oversimplified but this may be an important step so that ME/CFS Researchers...
Just wanted also to add, as shown on the figure 4C of the paper below, although not a strong signal, Tyrosine is being mentioned : [IMG]...
Good question. For the record, the techniques that i use agree with other mentions in the paper for Protein Kinase B (PKB) and Nf-kΒ pathway....
This is true and it’s been discussed in the text. I think that we must see the bigger picture since we have from previous research work from...
@Andy cc : @ScottTriGuy @JaimeS Making a correction / addition from other part of the text : and to be fair :
It gets more interesting with NRG1 : Alan and Kathleen Light have identified NRG1 and Peroxisome proliferator A (PPARA - identified during...
Please see this post for an association of NRG1 with Cholecystokinin (mentioned in the paper by McGowan et. al) , Vagus Nerve, Microglia...
cc : @ScottTriGuy @JaimeS As a short update, i am providing a new potential target for further Research on ME/CFS. We have a very interesting...
Some comments based on the "Liver Injury" hypothesis and given Dr. Light's presentation : A first note is that many people asked whether the...
@RDP Thank you posting here and for opening this channel of communication. The more i look at kynurenine / indoleamine, the more exciting it gets....
I am finding lately a lot of interesting connections between IDO1, Kynurenine, Ahr Receptor and CYP1A2, i wont get into that to avoid derailing...
Looking through the Liver Perspective, although i am not sure this is directly related :
cc : @JaimeS ,@ScottTriGuy , @Perrier Further to the hypothesis that ME/CFS originates from a Liver Injury caused by Viral Infection / Certain...
I would like to share some news about my talk with Dr Charles Shepherd regarding the Hypothesis that looks at Liver function. cc : @Andy Dr...
Here is a post about Liver Disease and its connection with NeuroInflammation and microglia activation for those of you who are interested :...
cc: @JaimeS @Andy H @Inara @Simon M @ScottTriGuy One more potential connection of Liver disease with Jarred Younger's findings in...
The Vagus nerve is identified by Machine Learning as important but i do not know why unfortunately. Given the signals i am getting from using it,...
Given epinephrine = Adrenaline = Catecholamines From a study in mice : and...
@Ravn TDO is highly expressed in the Liver : https://www.proteinatlas.org/ENSG00000151790-TDO2/tissue
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