Another limitation is that the studies in the review are mostly patients that have been sick in the range of 3-5 years or more, and there are...
I don't think there's anything to be gained from engaging with or paying attention to Garner in any way. He isn't some great authority, he's just...
I like how he talks about how the brain and body are the most complex in the whole universe, and then somehow manages to turn that into justifying...
The idea behind systematic reviews is essentially using systematic methods, such as GRADE and those outlined in the cochrane handbook of...
Evidence Synthesis is what cochrane does, ie. systematic reviews: https://www.cochrane.org/news/evidence-synthesis-what-it-and-why-do-we-need-it....
It's hard to comment on a specific case, but in other fatiguing conditions sleep usually almost completely ameliorates the fatigue, at least...
Nobody really seems to understand the ramifications of how the Royal Colleges stopped an independent evidence based guideline after already being...
This second piece demonstrates some of the issues with all of this. People are being asked to distrust people that they usually put a significant...
This just seems like more of an argument to use even stricter systematic methods, rather than give up on them altogether I agree. Some of the...
I suspect GRADE opts out there because claiming to be objective would be a very bold claim to make, and it still needs to be kept in mind that...
I think I agree with you that the pseudo-arithmetic borders a bit on being pseudoscientific. I still think you need some kind of strict systematic...
The idea behind methods like GRADE and systematic reviews is eliminating as much bias as possible in reviews of evidence. Hence why they need to...
So it seems like the two main reasons behind the royal colleges objections are the diagnostic criteria and the use of the GRADE system. Those are...
I don't think this is an exactly accurate portrayal of what they're saying. I think they're just saying that subjective measures were patient...
The rejection of GET and CBT in the NICE guideline was based on a number of different reasons beyond just the unblinded with subjective outcomes...
I think he's saying that stuff because the person he's replying to is saying people with ME can't exercise (rather than a more qualified or...
He may have meant a diagnostic criteria. NICE didn't recommend a specific diagnostic criteria, but just recommended looking for certain key symptoms
That makes some sense, his article does read a bit like he's trying to justify non-evidence based treatments under the guise of individualisation....
At least it's sympathetic to people with ME/CFS, and it calls for the guideline to be published
The NICE guideline still offers advice on management and support. That certainly is something.
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