I'm struck by how I've missed the point here i.e. impact of light, noise etc. [stimulus] on those severely ill with ME/CFS - particularly when...
As per my post above, I'm not aware of a (large/large enough) rare variant study i.e. by Ron Davis or anyone else. NIH - we'll perhaps know what...
Rare variant, whole genome sequence studies, look for low frequency (rare) variants which greatly increase risk of getting the disease (including...
One of the suggestions I've heard is to do whole genome sequence studies/rare variant studies on families with more than 1 member effected -...
Decided I'd make this comment* i.e. in response to the announcement** * **
Does someone wish to break this shocking discovery (joking) to the ME Association i.e. they could follow this protocol to monitor patients - they...
I know someone who is an NHS casualty Doctor (though they work through an agency - lots do!) they tell me that they're extremely careful i.e. to...
I searched the document* for a few key words (didn't read it) and noticed this - "Thane initially posted in a twitter thread about his situation:...
Jarred Younger is another person who may have MRS/MRI data re Glutamate levels, or at least would be able to check these findings.
I've very little knowledge but my understanding is that "Magnetic resonance spectroscopy (MRS)" or "MRI" is considered a reliable technique - just...
RELEVANT? I recall that Maureen Hanson highlighted that Andrew Grimson found platelets to be dysregulated** in ME/CFS potentially related to...
Which reminds me of Jonathan's comments re NICE Guideline "evidence" - mostly self interested professionals' saying -- "gizza job"
Interesting - any thoughts on who might fund this --? E.g. if it's a public body (UK Government funding) then it's deeply frustrating - surely a...
I think we need to be a little careful here - I (I've just retired) worked at a very junior level in policy development and well -- I recall a...
I was slightly concerned that those with ME/CFS might end up, like a friend who suffers with back pain has, with a tap on the head and some words...
Yea the gold is the ME Association funding --- shouldn't take too long to produce substandard work --- quid's in!
Not keeping up (as usual) had to Google "PROMs" - from the ME Association announcement of the study - "apply gold-standard techniques and develop...
Wondering if this could e.g. result in a signal in GWAS [common variants - low to modest effects] and/or rare variant genetic study (whole genome...
Noticed that Cort [Health Rising*] has just published an article on this [Mar 27, 2024] &...
I recalled these comments* from Vicky Whittemore re Wenzhong Xiao's talk (part of the metabolism webinar) - basically there are a lot of ways to...
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