Found this* by searching online [ME/CFS + NICE + core outcomes database]. On the face of it the body providing the funding to NHS England...
Back to the old question - Rituximab didn't work so ME/CFS is not an autoimmune disease; versus there could be long lived plasma cells which...
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Laughing - back to that @Brian Hughes cartoon ---- apart from the subjective outcome criteria ++++ not that bad a study! Whatever you do don't...
Jonathan Edwards's post here*, re TPPP1 gene, illustrates(?) a potential scenario i.e. a target gene/pathway is discovered and you run a...
Yea check out the Sheng Li, Ph.D. (Jackson Laboratory) talk (part of the NIH webinar series*) - note the slide states that the 1000 metabolite...
I was surprised that untargeted metabolomics hadn't provided leads. I think Dr. Li (Jackson Laboratory) suggested the data is fairly limited...
Googled & laughed!
Yip - I've put Paul down as cognitive dissonance [radio 4 program today*] I think there are £ signs in Fiona's claims ---...
Topic that comes up re Paul Garner etc- see blurb below* * 61. Brain Strain Sideways Rick Shenkman, a bright student and fervent supporter of...
Need to look at this presentation again, but I think the speaker highlighted the: poor metabolic coverage - currently most of the data is from...
Yea recall the outcome in Germany - roughly along these lines - "poorly understood diseases - unknown cause (etiology) & no treatments - with a...
Good point e.g. those who participated in the Nath NIH intramural study (lets forget Walitt!) could be tested to see whether they were considered...
Yea, probably difficult after NICE found the evidence to be "low" or "very low" quality. Well done to those involved in achieving that result.
Bit cruel but --- :laugh:
I'm struck that Wessely's arguments are well constructed - they're still just crap. Science is basically about measuring things - as per Kelvin*....
I watched Dr. Shuzhao Li (associate professor investigator - Jackson Laboratory) presentation metabolism webinar "The interplay between Metabolism...
Folks - my request for - whole genome sequence/rare variant study looks like a larger version of this family study by Fereshteh Jahanbani -...
Good idea i.e. there may be circumstances where it's useful to highlight the rational for a particular suggestion.
I received this reply from NIH/Vicky* - not actually surprised i.e. it's consistent with my impression of Vicky - pragmatism +++. Hopefully I'll...
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