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  1. Lucibee
    Post

    A general thread on the PACE trial!

    This was in the Protocol: ETA: Date of approval was 31 Mar 2003 according to http://www.isrctn.com/ISRCTN54285094
    Post by: Lucibee, Dec 2, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  2. Lucibee
    Post

    A general thread on the PACE trial!

    Fair enough. However, their actual results (per protocol) fell a long way short of the assumptions for the trial:
    Post by: Lucibee, Dec 2, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  3. Lucibee
    Post

    A general thread on the PACE trial!

    Interesting that Hotopf's review abstract makes the point that this is improvement *without* any systematic intervention, so to find such a poor...
    Post by: Lucibee, Dec 1, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  4. Lucibee
    Post

    A general thread on the PACE trial!

    Thanks @Tom Kindlon . I had misremembered. It was improvement they looked at. The results are somewhat affected by their definition of...
    Post by: Lucibee, Dec 1, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  5. Lucibee
    Post

    A general thread on the PACE trial!

    Interesting that the top 2 items under "Latest news" have lost their links now... I seem to remember that analysis getting pretty similar...
    Post by: Lucibee, Nov 30, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  6. Lucibee
    Post

    2018: Discussion on the NICE procedure: what to expect next?

    Thanks! Nearly 600 pages of general comments! Wow! https://www.nice.org.uk/guidance/cg53/documents/general-table-of-comments2
    Post by: Lucibee, Nov 29, 2018 in forum: 2020 UK NICE ME/CFS Guideline
  7. Lucibee
    Post

    2018: Discussion on the NICE procedure: what to expect next?

    Are these comments still available on the NICE website somewhere?
    Post by: Lucibee, Nov 29, 2018 in forum: 2020 UK NICE ME/CFS Guideline
  8. Lucibee
    Post

    When a Placebo Is Not a Placebo: Problems and Solutions to the Gold Standard in Psychotherapy Research (2018) Blease et al.

    I guess it's all in the comparison. Psych trialists want the comparison to be as big as possible to maximise the effect they see. But from a RCT...
    Post by: Lucibee, Nov 27, 2018 in forum: Research methodology news and research
  9. Lucibee
    Post

    When a Placebo Is Not a Placebo: Problems and Solutions to the Gold Standard in Psychotherapy Research (2018) Blease et al.

    @Barry I would agree with most of that, but psychological treatments should not be given a free pass on this one. RCTs could be better designed...
    Post by: Lucibee, Nov 27, 2018 in forum: Research methodology news and research
  10. Lucibee
    Post

    Reply from Nice

    [MEDIA]
    Post by: Lucibee, Nov 22, 2018 in forum: General ME/CFS news
  11. Lucibee
    Post

    NICE guideline review: A list of appointees to the ME/CFS Guideline Committee has now been published

    [MEDIA]
    Post by: Lucibee, Nov 22, 2018 in forum: 2020 UK NICE ME/CFS Guideline
  12. Lucibee
    Post

    Who was it that said being in support groups leads to poor outcome?

    @JaimeS - I don't think you can sum the deltas like that. Those categories are not necessarily mutually exclusive.
    Post by: Lucibee, Nov 22, 2018 in forum: General Advocacy Discussions
  13. Lucibee
    Post

    Who was it that said being in support groups leads to poor outcome?

    Percentages, I think.
    Post by: Lucibee, Nov 22, 2018 in forum: General Advocacy Discussions
  14. Lucibee
    Post

    David Tuller: Trial By Error: Some Thoughts About NICE

    Well if she does insist on blocking the "new kids", we won't ever be able to listen!
    Post by: Lucibee, Nov 20, 2018 in forum: General ME/CFS news
  15. Lucibee
    Post

    A general thread on the PACE trial!

    Oh good. At least they got your informed consent to participate then... :facepalm:
    Post by: Lucibee, Nov 12, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  16. Lucibee
    Post

    A general thread on the PACE trial!

    If you knew which arm you were in, it wasn't properly blinded.
    Post by: Lucibee, Nov 12, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  17. Lucibee
    Post

    Who said: don't bother testing patients?

    I'm wondering if anyone has systematically tracked the trail of misinformation that the likes of Wessely, White, Sharpe, Manu etc have left in...
    Post by: Lucibee, Nov 12, 2018 in forum: General ME/CFS news
  18. Lucibee
    Post

    New Zealand: Dr Vallings

    Wessely planted his 'get-out clause' on this nearly 20 years ago: https://www.ncbi.nlm.nih.gov/pubmed/10616232 [It's #107 in the Wessely files,...
    Post by: Lucibee, Nov 12, 2018 in forum: Other clinics and doctors
  19. Lucibee
    Post

    A general thread on the PACE trial!

    There were so many problems with the original protocol anyway, I'm really not sure it makes much difference. We sometimes get a bit obsessed that...
    Post by: Lucibee, Nov 11, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
  20. Lucibee
    Post

    A general thread on the PACE trial!

    Arguably that could create more bias, not less. CGI and attendance, although filled in on anonymised forms, was recorded by the therapist - they...
    Post by: Lucibee, Nov 11, 2018 in forum: Psychosomatic research - ME/CFS and Long Covid
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