Severe PEMs that last months feel like that in my experience. And it does take some time for me to get back to the baseline after the PEM is over....
For what it's worth, I view symptoms and threshold imposed by worsening of symptoms as two different things. If I know that I'm not going to get...
I'm in bed with one right now, for the second time in 3 years. No, I haven't got it tested; I'm away from my other home and don't have access to...
I think PEM is hypersensitivity to the process of repairing the damage from exertion. Some exerkines/myokines may be relevant in that they are...
I personally think this is a more likely explanation, assuming Younger's result stands. Things like allergies or chronic stress have been...
There is no proof that muscle functioning is responsible for your symptoms. Most patients can push through when they are not in PEM. It's just...
Depending on what you mean by "recover" and "improve". People do recover after minor PEMs that last several days. And they do improve in terms of...
It would've been nice if they used ME/CFS patients as the control. It says ".. a reduction in day 2 was suggested to be the result of PEM", so we...
I may fall in that category, at least when I'm on the road. I can climb mountains as well as anybody, till I try to push my pace and pay the price...
I would think that is possible, though I'm not sure what that would prove. DOMS is caused by microtear, or, more precisely, by the immune system...
I don't know what Carson said, but it would be wrong if anybody said PEM is DOMS or vice versa. Nobody here is saying that PEM is DOMS or vice...
I think this is the crux of ME/CFS patients needing to lie down that @Jonathan Edwards talked about. Just sitting up is an exertion enough that...
I hear you. I can even believe some people experiencing PEM just from being alive and breathing. I believe that is what severely ill people with...
And my/our interest would be how OTS/LC intersects ME/CFS rather than managing/researching OTS/LC themselves. If we are to wait for satisfactory...
Yes, DOMS is a local symptom. But the same exercise-response that leads to DOMS could be precipitating PEM in ME/CFS.
A quarter glass of wine used increase my head pressure and I'd get knocked out in about 30 min with debilitating fatigue. These days, I can...
I've been suspecting some parallel for a long time too. There was a paper that said PEM is not DOMS because they didn't find micro-tear in muscle...
Overtraining/overreaching syndrome is relatively rare compared to post-viral syndrome (since its prevalence is usually sports-related), and it...
It could well be normal fatigue if you are severely deconditioned, or a fatigue from other condition. Socializing for a few hours can actually be...
It took 9 days this time to recover from a long trip, a bit longer than usual: 8 hours spent lying down, then 5 and then finally back down to 2-3....
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