Isn't it the case that we all experience worsening of symptoms 12-48 hours after an exertion over certain threshold? I understand that there are...
Sounds like we have problem with the concept of "concept". Why don't we fall back to the common usage of it, "an (abstract) idea"? You may be...
"Syndrome" may be a concept the same way "disease" is. But I don't think you need to know the underlying mechanism to identify the disease as...
I come from computer background where names are just handles. Etymology may be important in a real language, but the meaning of words often change...
Not sure if that is generally true. Personally, I've been sleeping like a baby ever since I got ME/CFS. It's just that sleep doesn't improve my...
That's not what Walitt paper says though. It used 1-day CPET test as evidence that patients are capable of exerting, but patients are choosing,...
I don't quite understand what this paper is trying to accomplish. Aren't we well past the concept stage with ME/CFS? ME/CFS is not a concept; it...
I think people should stop clamoring for specialist care or treatment, and instead focus on research. There isn't anything anybody, specialists or...
A wild speculation by someone who haven't got a foggiest idea what PEM is. If he asked MECFS patients in early stage why they describe PEM as...
I'm trying to remember what kept me horizontal when I was in the depth of MECFS. One was what many MECFS patients describe as "profound...
Maybe, maybe not. The symptomatic manifestation could be radically different for similar underlying processes, especially when the brain is...
Did it? I thought they only discovered correlation between the performance and DOPAC and DHPG in MECFS patients while there was no such...
Externally imposed variations need to be controlled though. Come to think of it, mecfs patients could've had low variations than they should've...
All the studies mentioned in the blog are 3-12 days long. Not sure if you can discern push/crash pattern in a such short observations. Good days...
Yet another study pointing to neuroinflammation and BBB breach caused by peripheral inflammation. But it still doesn't explain LC that persists...
Pretty ingenious experiment. But proving something is sufficient is not much of a value. Proving it necessary is. They can't point to microglia as...
Nath, the guy who wanted RECOVER to start with a clean slate, is obviously still making distinction between LC and MECFS. He is intent on again...
I don't even "understand" my sick self when I'm healthy. I have to concentrate and visualize to recall my feelings and struggles. Given that, I...
Hypochondriacs posting in an online LC group doesn't make them an LC patient. The title of the paper should be changed to "Reddit user’s...
That's what fatigue is in exercise to failure: your muscles can no longer generate power to move the weight another inch.
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