I would argue this just means such a test with less than 95% clinical agreement is more scientifically interesting, we can learn more from it,...
Yes, I am very intrigued with the preload failure as it fits with cardiac research in ME going back nearly two decades, or more. I think Cneney...
Which just means it needs much more development to be used as a valid test, not that it is not an hypthetical test. However if its only found in...
Or a bunch of different diseases, but yes, figuring out causal mechanisms is good for figuring out biomarkers, but we also need biomarkers to...
I actually regard that as evidence that to move forward either we abandon it or use a diagnostic test. Since we have a putative test it can be...
That does not make it useless, for several reasons. First, fibro diagnoses are often hotly disputed, and a diagnostic test therefore has both...
Specificity is always an issue until long after its in use clinically and we can see results. Jonathon mentions the 95% specificity and...
1988 "of objectively measuring the muscle (and mental) fatigue that is its hallmark" 1940 Tilt table test 1946 Quantitative EEG 1949 CPET They...
Again, my assertion is they indulge in persuasive rhetoric, not evidence and reason. Its about a particular medical subculture. Psychiatry in...
I started with mild ME, and went undiagnosed for perhaps decades. I kept pushing myself, exercising, and never came to an understanding of my...
Yes, something like that I would expect to see in time.
Workwell seems to be currently focused on increasing non-aerobic exercise to tolerance. This is work in progress, and I expect their exercise...
Its not clear. Some parasites, much larger, are almost impossible to find. It depends on numbers, locations, and lifecycle. If they rarely enter...
I have a reply for positive thinkers these days, keep your religion to yourself.
... or pink fuzzy aliens. Or those damn flesh eating unicorns, they are everywhere. (PS I was thinking about a quote from a game that I like, "A...
The two hit hypothesis is about having one infection impacted by another. Its why incubation times in ME pandemics might not reflect the actual...
I was born in Malaya before it federated, so I guess I am an army brat. I passed through Lebanon briefly when a plane was diverted due to active...
Doh, what trypanosome does at a molecular level I have linked to ME symptoms many times in many discussions. Its about modifying a specific...
PACE, SMILE, FINE, do you see a pattern? They always do this.
I have said elsewhere that using technical definitions of things that are vastly different from the usual then rarely clarifying is their modus...
Separate names with a comma.
