If you take "mind" out of the discussion, and focus on brain, stimuli, brain changes, physiological changes, you can avoid the traps psychogenic...
Not at all. Emotional and experiential events induce brain changes. Brain changes can lead to things including depression. Brains do react to...
Having an uncurable chronic condition which can be highly debilitating, no useful medical support, scorn from family and support systems, that...
I have had an interest in this area for a long time, largely because of the cAMP/Ca++ axis, and resveratrol. One of the drugs under invesigation...
Yes.
Yes, but the highest concentration of oxidative stress as free radicals would be inside the mitochondria. Furthermore, these proteins are folded...
Proper folding of proteins requires reduced glutathione. Oxidative stress or glutathione deficiency (including potentially cofactor depletion like...
So far as I am aware the creation of such cultures is a well established thing. I am unsure about brain cells though. Tissue cultures allow a lot...
Both regular medicine and alternative medicine have risks. Some forms of alternative medicine are just dangerous with no mitigating effects, just...
Doctors have faced the death penalty, I think, for similarly dangerous practices (laetrile), at least in the USA.
The evidence is moderately strong that something in the blood is large molecule size, which might include vesicles, and mediates cellular energy...
I suspect the nanoneedle test will NOT distinguish ME/CFS from mitochondrial disorders. However it may be that the existing diagnostic protocols,...
Correct, but misleading. With a target that may be a mediating step for our energy loss we can develop new drugs, repurpose old ones like the SS...
I would really like people with mitochondrial disorders to be tested. No salt response, full response, or mixed response would all tell us...
Its the objective outcome in scientific studies that is indeed lacking. Its only been since about 2007 that this idea has started to be pursued....
They avoid this like the plague. EVERY study that uses objective outcomes for CBT/GET has failed, either showing no benefit or a decrease in capacity.
I think we have enough evidence now to be talking about the response to energy demand, not just exercise. This might also include immunological,...
LORETA software is used in quantitative EEG, which is confirmed in the article. It shows major abnormalities in ME according to the limited...
One of the issues with calcium channel changes is changes to intracellular calcium. If there are any it might mess with the calcium-cyclic AMP...
I have not read the paper yet, but it seems to me that this paper may just raise questions, not provide answers. GWI also does not have a...
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