for what it's worth I also saw overexpressed proteasome complex subunits in LCLs from pwME in my PhD work
Pretty sure there are dozens of papers showing it to correlate with reduced survival in human cancer patients
I think there is immunotyping coming up in the larger studies which would be good They are close together on the chromosome so it is likely that...
Cohort is too small to subdivide and get much meaningful out of it, I think. Certainly, stats aren't going to work. Important for future...
Very exciting. I should also clarify that a lot of the work happening is not just that driven by us or our study here. So many researchers are...
I have noticed that the abstract is cooked (words mashed together several times) no idea whether this came from the journal or from changes of...
I have seen lipid homeostasis issues in cells from multiple tissues from pwME (some of these are experiments with Chris) and I do want to...
I remember Kathy presenting this at stony brook last year, talking with her afterwards and being very impressed, good to see it landing in an...
Thanks for sharing - all good now I think. Sarah is preparing two different projects for different grants at the moment and I believe that her PPI...
probably time since infection/onset being much shorter in LC than ME? (I havent seen their cohort data or if they include duration of illness tho)...
I agree that for interpreting function a deeper dive into specific genes needs to be done. Getting a GO hit for "cytoplasm" for example means...
This is where my brain went as well but a google seems to suggest it is referring to a type of breathing exercise. Doesn't seem easy to find...
Thank you to those who are ready to go for home visits. Look forward to meeting you all in a month or so. We are still a little short of targets...
"Human plasma samples were collected from 38 patients with ME/CFS, consisting of 27 females and 11 males, with an average age of 43 years (±13)....
Still recruiting due to individuals who satisfied exclusion criteria. Timeline update: Due to some mass spec training this week, I will start...
How does one resolve such ascertainment problems? Are you saying that current case criteria are unreliable, or that the rigor of their...
Emily Eriksson is an investigator in our current ME/CFS Mason study. It will be good to translate her expertise to ME
If you install realstats addin for excel and use the formulae as in the paper, it will do everything for you automatically so you need not worry...
you can test for normality and test for equality of variances and then triage each feature to different tests depending on whether...
:banghead: Indeed!
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