Hanson group has just published a paper looking at them, how timely :D
A text mining model once pointed at one thing (amongst many things), that also popped up in this study (as one of many things) and this...
https://www.google.com/search?q=mbl+deficiency+prevalence&rlz=1C1ONGR_en-GBAU995AU995&oq=mbl+deficiency+prevalence&aqs=chrome..69i57.275j0j1&source...
EVs are a field very much in vogue at the moment so expect a lot more in this direction is my guess
Generally speaking yes but depends on specifics of: 1) is the signal being measured detectable in the other particular cell type. Eg: mito...
Okay, I have answers! Yay. 1) Aspects of fibroblast cell culture that I raised appear to be handled sensibly, carefully, thoroughly and...
Paul Hwang sent me a couple of lovely responses, seems like a really nice guy. I didn't get the full picture because he's out of the office and my...
@chillier thanks for asking for detail and holding my statements accountable. Should actually happen more. Density (contact inhibition): I don't...
I see that we may be having similar friendly conversations away from s4me :D very exciting To add my own experience: we did not see an effect of...
I think of it as: DNA is the blueprint, mRNA is a photocopy of the blueprint sent to the factory floor, protein is what the photocopy tells the...
I do, and I agree and am currently playing with it, but the information is sadly incomplete because we don't have access to the patient records of...
Interesting. The lipidomics I presented at IACFSME 2023 showed broadly elevated levels of lipids in lymphoblastoid cell lines generated from pwME.
I really hope this is an English issue more than somebody walking in and just defining the disease into their existing research box.
The bottom line with prospective markers is that nothing has been properly revisited and validated in publication since the wave of modern...
You don't need to qualify your questions before asking :). Thanks for engaging in such a great way with your thoughts and questions. There are a...
I want to look at muscle but it's just been so practically challenging. Getting enough material to do the extent of in-depth experiments that I do...
Thanks for the link to relevant discussion. I went down the rabbit hole from your link, and saw some s4me chatter about the unlikelihood that a...
Thank you for the clarification @Jonathan Edwards, I think I misconstrued one or two elements of your post. I agree with your frustrations...
Not mutually exclusive. Also, yes, if a biological feature being used as a diagnostic is one that's related to the underlying causal mechanism,...
Whole blood mito material will be affected by muscle damage due to physical activity, was physical activity prior to sampling, per individual,...
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